R222Q SCN5A mutation is associated with reversible ventricular ectopy and dilated cardiomyopathy
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Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 ComparisonOmega pore, an alternative ion channel permeation pathway involved in the development of several channelopathiesHighlights of the year in JACC 2012Cellular hyper-excitability caused by mutations that alter the activation process of voltage-gated sodium channelsAberrant sodium influx causes cardiomyopathy and atrial fibrillation in miceGenetics and disease of ventricular muscle.Beyond the Electrocardiogram: Mutations in Cardiac Ion Channel Genes Underlie Nonarrhythmic Phenotypes.Novel SCN5A mutation in amiodarone-responsive multifocal ventricular ectopy-associated cardiomyopathy.Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy.Electrophysiological characteristics of a SCN5A voltage sensors mutation R1629Q associated with Brugada syndromeNext-generation sequencing for the diagnosis of cardiac arrhythmia syndromes.Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx (5cv) mice.A1180V of cardiac sodium channel gene (SCN5A): is it a risk factor for dilated cardiomyopathy or just a common variant in Han Chinese?A systematic approach to assessing the clinical significance of genetic variants.Mendelian forms of structural cardiovascular disease.Genetic testing in cardiovascular diseases.Biophysics, pathophysiology, and pharmacology of ion channel gating pores.A Review of the Potential Pathogenicity and Management of Frequent Premature Ventricular Contractions.Antiarrhythmic Action of Flecainide in Polymorphic Ventricular Arrhythmias Caused by a Gain-of-Function Mutation in the Nav 1.5 Sodium Channel.Nav 1.5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link?Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy.Aberrant sialylation causes dilated cardiomyopathy and stress-induced heart failure.In Silico Evaluation of the Potential Antiarrhythmic Effect of Epigallocatechin-3-Gallate on Cardiac Channelopathies.Mutations in the Voltage Sensors of Domains I and II of Nav1.5 that are Associated with Arrhythmias and Dilated Cardiomyopathy Generate Gating Pore Currents.Cardiac Arrhythmias Related to Sodium Channel Dysfunction.Targeted next generation sequencing in a young population with suspected inherited malignant cardiac arrhythmias.Dilated Cardiomyopathy: Genetic Determinants and Mechanisms.Sinus Bradycardia in Carriers of the SCN5A-1795insD Mutation: Unraveling the Mechanism through Computer Simulations.Rapid and effective response of the R222Q SCN5A to quinidine treatment in a patient with Purkinje-related ventricular arrhythmia and familial dilated cardiomyopathy: a case report.Gating Pore Currents in Sodium ChannelsVariants: Association With Cardiac DisordersA leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy
P2860
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P2860
R222Q SCN5A mutation is associated with reversible ventricular ectopy and dilated cardiomyopathy
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@ast
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@en
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@nl
type
label
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@ast
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@en
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@nl
prefLabel
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@ast
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@en
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@nl
P2093
P3181
P1476
R222Q SCN5A mutation is associ ...... opy and dilated cardiomyopathy
@en
P2093
Anu Aggarwal
David Playford
Dennis Kuchar
Diane Fatkin
Guanglan Guo
Kathryn Stockhammer
Maria L Castro
Monique Ohanian
Poonam Zodgekar
Rajesh Subbiah
P304
P3181
P356
10.1016/J.JACC.2012.05.050
P407
P577
2012-09-19T00:00:00Z