p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
about
Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotypeThe cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growthThe novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanomaHyperforin inhibits Akt1 kinase activity and promotes caspase-mediated apoptosis involving Bad and Noxa activation in human myeloid tumor cells.Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.Mechanisms of apoptosis on human lens epithelium after ultraviolet light exposure.Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.Rationally designed treatment for solid tumors with MAPK pathway activation: a phase I study of paclitaxel and bortezomib using an adaptive dose-finding approach.Restoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stressSynergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer.Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin.γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.Notch signaling promotes growth and invasion in uveal melanoma.EphA2 as a promoter of melanoma tumorigenicitySensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN statusThe role of miR-18b in MDM2-p53 pathway signaling and melanoma progressionMelanocyte receptors: clinical implications and therapeutic relevance.Understanding signaling cascades in melanomaMechanisms and clinical prospects of Notch inhibitors in the therapy of hematological malignancies.Wnt and related signaling pathways in melanomagenesis.The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibition.Active Notch1 confers a transformed phenotype to primary human melanocytes.Bcl2 family proteins in carcinogenesis and the treatment of cancer.Combining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments.Developmental pathways activated in melanocytes and melanoma.Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis.Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms.Noxa and cancer therapy: Tuning up the mitochondrial death machinery in response to chemotherapy.PAX3-FOXO1 induces up-regulation of Noxa sensitizing alveolar rhabdomyosarcoma cells to apoptosis.Notch1 is an effector of Akt and hypoxia in melanoma development.Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways.ALK-negative anaplastic large cell lymphoma is sensitive to bortezomib through Noxa upregulation and release of Bax from Bcl-2.
P2860
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P1343
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P2860
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@ast
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@en
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@nl
type
label
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@ast
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@en
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@nl
prefLabel
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@ast
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@en
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@nl
P2093
P4510
P1476
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
@en
P2093
Amy Curtis
Barbara Bodner
Brian J Nickoloff
Elisabeth A Seftor
Frank Bennett
Jeffrey M Trent
Jian-Zhong Qin
Lawrence Stennett
Lucio Miele
Mary J C Hendrix
P304
P407
P577
2004-08-01T00:00:00Z