An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors - Wikidata - awgldk - TriplyDB

An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

http://www.wikidata.org/entity/Q28276070

about

Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation Crystallographic insight into collagen recognition by discoidin domain receptor 2 Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family A urokinase receptor-associated protein with specific collagen binding properties Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1 Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1 Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation Structural basis of the collagen-binding mode of discoidin domain receptor 2 Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure Cell signaling by receptor tyrosine kinases Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice Developmental and pathogenic mechanisms of basement membrane assembly Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis Discoidin Domain Receptors: Potential Actors and Targets in Cancer Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling Structural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase Inhibitors Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.Discoidin domain receptor 1 is activated independently of beta(1) integrin Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen Mammalian collagen IV Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants Decorin is a biological ligand for the epidermal growth factor receptor The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism.Keratocan, a cornea-specific keratan sulfate proteoglycan, is regulated by lumican Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons Endo180 binds to the C-terminal region of type I collagen Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2 Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2 Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3)How matrix metalloproteinases regulate cell behavior Suppression of discoidin domain receptor 1 expression enhances the chondrogenesis of adipose-derived stem cells.Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway.Collagen XV inhibits epithelial to mesenchymal transition in pancreatic adenocarcinoma cells.A novel mutation in DDR2 causing spondylo-meta-epiphyseal dysplasia with short limbs and abnormal calcifications (SMED-SL) results in defective intra-cellular trafficking.

P2860

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P2860

An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

http://www.wikidata.org/entity/Q28276070

description

1997 nî lūn-bûn

@nan

1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1997年の論文

@ja

1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

name

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@ast

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@en

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@nl

type

label

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@ast

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@en

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@nl

prefLabel

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@ast

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@en

An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@nl

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An orphan receptor tyrosine ki ...... nonintegrin collagen receptors

@en

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A Shrivastava

http://www.w3.org/2001/XMLSchema#string

C Radziejewski

http://www.w3.org/2001/XMLSchema#string

D J Glass

http://www.w3.org/2001/XMLSchema#string

E Campbell

http://www.w3.org/2001/XMLSchema#string

G D Yancopoulos

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G Lemke

http://www.w3.org/2001/XMLSchema#string

L Kovac

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M McGlynn

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M P Goldfarb

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S Davis

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25-34

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scholarly article

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4701899

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10.1016/S1097-2765(00)80004-0

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1

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9659900

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