Decorin is a biological ligand for the epidermal growth factor receptor - Wikidata - awgldk - TriplyDB

Decorin is a biological ligand for the epidermal growth factor receptor

Decorin is a biological ligand for the epidermal growth factor receptor

http://www.wikidata.org/entity/Q28297196

about

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan Decorin causes autophagy in endothelial cells via Peg3 Calcium efflux activity of plasma membrane Ca2+ ATPase-4 (PMCA4) mediates cell cycle progression in vascular smooth muscle cells Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells Mammographic density is related to stroma and stromal proteoglycan expression Oncosuppressive functions of decorin Antiangiogenic mechanisms and factors in breast cancer treatment Decorin: A Growth Factor Antagonist for Tumor Growth Inhibition Decoding the Matrix: Instructive Roles of Proteoglycan Receptors Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion Biological interplay between proteoglycans and their innate immune receptors in inflammation Pivotal role for decorin in angiogenesis Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope Lumican deficiency results in cardiomyocyte hypertrophy with altered collagen assembly Topological analysis of small leucine-rich repeat proteoglycan nyctalopin Keratocan, a cornea-specific keratan sulfate proteoglycan, is regulated by lumican Lumican binds ALK5 to promote epithelium wound healing Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan.Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin.Age-related changes in the proteoglycans of human skin. Specific cleavage of decorin to yield a major catabolic fragment in adult skin.Antisense inhibition of decorin expression in myoblasts decreases cell responsiveness to transforming growth factor beta and accelerates skeletal muscle differentiation.Biologically active decorin is a monomer in solution.Differential expression and localization of decorin in human choriodecidual membrane during preterm and term pregnancy.The Extracellular Matrix in Epithelial Ovarian Cancer - A Piece of a Puzzle.Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation Effects of dietary physical or nutritional factors on morphology of rumen papillae and transcriptome changes in lactating dairy cows based on three different forage-based diets Decorin differentially modulates the activity of insulin receptor isoform A ligands.Decorin deficiency promotes hepatic carcinogenesis Maternal bias and escape from X chromosome imprinting in the midgestation mouse placenta.Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology Soluble biglycan as a biomarker of inflammatory renal diseases.Nanotechnology and adeno-associated virus-based decorin gene therapy ameliorates peritoneal fibrosis Increased expression of chondroitin sulphate proteoglycans in rat hepatocellular carcinoma tissues.Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans Target-seeking antifibrotic compound enhances wound healing and suppresses scar formation in mice.Decorin treatment of spinal cord injury Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesis

P2860

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P2860

Decorin is a biological ligand for the epidermal growth factor receptor

http://www.wikidata.org/entity/Q28297196

description

1999 nî lūn-bûn

@nan

1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

1999年の論文

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1999年論文

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1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Decorin is a biological ligand for the epidermal growth factor receptor

@ast

Decorin is a biological ligand for the epidermal growth factor receptor

@en

Decorin is a biological ligand for the epidermal growth factor receptor

@nl

type

label

Decorin is a biological ligand for the epidermal growth factor receptor

@ast

Decorin is a biological ligand for the epidermal growth factor receptor

@en

Decorin is a biological ligand for the epidermal growth factor receptor

@nl

prefLabel

Decorin is a biological ligand for the epidermal growth factor receptor

@ast

Decorin is a biological ligand for the epidermal growth factor receptor

@en

Decorin is a biological ligand for the epidermal growth factor receptor

@nl

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Journal of Biological Chemistry

P1476

Decorin is a biological ligand for the epidermal growth factor receptor

@en

P2093

D J McQuillan

http://www.w3.org/2001/XMLSchema#string

D K Moscatello

http://www.w3.org/2001/XMLSchema#string

I Eichstetter

http://www.w3.org/2001/XMLSchema#string

P2860

The discoidin domain receptor tyrosine kinases are activated by collagen

High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule

An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

Matrix proteoglycans: from molecular design to cellular function

The core protein of the chondroitin sulfate proteoglycan phosphacan is a high-affinity ligand of fibroblast growth factor-2 and potentiates its mitogenic activity

Specific inhibition of type I and type II collagen fibrillogenesis by the small proteoglycan of tendon

De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells

Receptors for epidermal growth factor and other polypeptide mitogens.

Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture.

Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition.

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4489-4492

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scholarly article

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10.1074/JBC.274.8.4489

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8

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P478

274

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Renato V. Iozzo

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1999-02-01T00:00:00Z

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13300140

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