Prothrombinase complex assembly. Contributions of protein-protein and protein-membrane interactions toward complex formation

Prothrombinase complex assembly. Contributions of protein-protein and protein-membrane interactions toward complex formation

Item
http://www.wikidata.org/entity/Q28276354
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilisAn anticoagulant RNA aptamer that inhibits proteinase-cofactor interactions within prothrombinaseRegulated cleavage of prothrombin by prothrombinase: repositioning a cleavage site reveals the unique kinetic behavior of the action of prothrombinase on its compound substrateInhibition of thrombin formation by active site mutated (S360A) activated protein C.Notecarin D binds human factor V and factor Va with high affinity in the absence of membranes.A bipartite autoinhibitory region within the B-domain suppresses function in factor VPhosphatidylserine-induced factor Xa dimerization and binding to factor Va are competing processes in solution.Membrane binding by prothrombin mediates its constrained presentation to prothrombinase for cleavageMembrane-dependent interaction of factor Xa and prothrombin with factor Va in the prothrombinase complex.Restoring the procofactor state of factor Va-like variants by complementation with B-domain peptidesAmino acid region 1000-1008 of factor V is a dynamic regulator for the emergence of procoagulant activity.Mapping of the factor Xa binding site on factor Va by site-directed mutagenesisFate of membrane-bound reactants and products during the activation of human prothrombin by prothrombinase.Cooperative regulation of the activity of factor Xa within prothrombinase by discrete amino acid regions from factor Va heavy chain.Prothrombin kringle 1 domain interacts with factor Va during the assembly of prothrombinase complex.Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va.Minor Plasma Lipids Modulate Clotting Factor Activities and May Affect Thrombosis Risk.
P2860

Prothrombinase complex assembly. Contributions of protein-protein and protein-membrane interactions toward complex formation

Item
http://www.wikidata.org/entity/Q28276354
description
1990 nî lūn-bûn
@nan
1990 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի մարտին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Prothrombinase complex assembl ...... tions toward complex formation
@ast
Prothrombinase complex assembl ...... tions toward complex formation
@en
Prothrombinase complex assembl ...... tions toward complex formation
@nl
type
label
Prothrombinase complex assembl ...... tions toward complex formation
@ast
Prothrombinase complex assembl ...... tions toward complex formation
@en
Prothrombinase complex assembl ...... tions toward complex formation
@nl
prefLabel
Prothrombinase complex assembl ...... tions toward complex formation
@ast
Prothrombinase complex assembl ...... tions toward complex formation
@en
Prothrombinase complex assembl ...... tions toward complex formation
@nl
P1433
P1476
P2093
P304
P31
P407
P433
P478
P577
P698
P1433
P1476
Prothrombinase complex assembl ...... tions toward complex formation
@en
P2093
P304
P31
P407
P433
P478
P577
P698