Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth
about
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductaseConservation between human and fungal squalene synthetases: similarities in structure, function, and regulationThe biological role of dolicholCloning, expression, and characterization of cDNAs encoding Arabidopsis thaliana squalene synthaseMolecular cloning and characterization of the yeast gene for squalene synthetaseCloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinaseExtraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesiclesOptimizing Treatment of Familial Hypercholesterolemia in Children and AdolescentsRecent technical developments in the study of ER-associated degradationDual functions of Insig proteins in cholesterol homeostasisCoordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptakeStructural Basis for Regulation of the Human Acetyl-CoA Thioesterase 12 and Interactions with the Steroidogenic Acute Regulatory Protein-related Lipid Transfer (START) DomainCompetition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression.Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductaseIdentifying mutations in duplicated functions in Saccharomyces cerevisiae: recessive mutations in HMG-CoA reductase genesOptional exon in the 5'-untranslated region of 3-hydroxy-3-methylglutaryl coenzyme A synthase gene: conserved sequence and splicing pattern in humans and hamstersPlasma mevalonate as a measure of cholesterol synthesis in manNeutrophils are required for the DNA synthetic response of human lymphocytes to mevalonic acid: evidence suggesting that a nonsterol product of mevalonate is involvedHuman SCARB2-mediated entry and endocytosis of EV71Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteinsCloning and regulation of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme in bile acid biosynthesisMolecular cloning of mevalonate kinase and regulation of its mRNA levels in rat liverRegulation of cytosolic 3-hydroxy-3-methylglutaryl-CoA synthase mRNA levels by L-tri-iodothyronineMolecular cloning and sequence of a cholesterol-repressible enzyme related to prenyltransferase in the isoprene biosynthetic pathwayDiurnal rhythm of rat liver cytosolic 3-hydroxy-3-methylglutaryl-CoA synthaseParasympathetic response in chick myocytes and mouse heart is controlled by SREBPBeclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm laborBrain cholesterol turnover required for geranylgeraniol production and learning in mice.Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging.Expression of the Arabidopsis HMG2 gene, encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase, is restricted to meristematic and floral tissues.Dynamical modeling of the cholesterol regulatory pathway with Boolean networks.In vitro screening for β-hydroxy-β-methylglutaryl-CoA reductase inhibitory and antioxidant activity of sequentially extracted fractions of Ficus palmata Forsk.Current development in isoprenoid precursor biosynthesis and regulationAn LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain CancersSequential actions of the AAA-ATPase valosin-containing protein (VCP)/p97 and the proteasome 19 S regulatory particle in sterol-accelerated, endoplasmic reticulum (ER)-associated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.3-Hydroxy-3-methylglutaryl-coenzyme A reductase from Arabidopsis thaliana is structurally distinct from the yeast and animal enzymes.Induction of the cholesterol metabolic pathway regulates the farnesylation of RAS in embryonic chick heart cells: a new role for ras in regulating the expression of muscarinic receptors and G proteinsSterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets.Isoprenoids, small GTPases and Alzheimer's disease.Cholesterol metabolism is altered in Rett syndrome: a study on plasma and primary cultured fibroblasts derived from patients.
P2860
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P2860
Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth
description
1980 nî lūn-bûn
@nan
1980 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1980 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1980年の論文
@ja
1980年論文
@yue
1980年論文
@zh-hant
1980年論文
@zh-hk
1980年論文
@zh-mo
1980年論文
@zh-tw
1980年论文
@wuu
name
Multivalent feedback regulatio ...... noid synthesis and cell growth
@ast
Multivalent feedback regulatio ...... noid synthesis and cell growth
@en
Multivalent feedback regulatio ...... noid synthesis and cell growth
@nl
type
label
Multivalent feedback regulatio ...... noid synthesis and cell growth
@ast
Multivalent feedback regulatio ...... noid synthesis and cell growth
@en
Multivalent feedback regulatio ...... noid synthesis and cell growth
@nl
prefLabel
Multivalent feedback regulatio ...... noid synthesis and cell growth
@ast
Multivalent feedback regulatio ...... noid synthesis and cell growth
@en
Multivalent feedback regulatio ...... noid synthesis and cell growth
@nl
P1476
Multivalent feedback regulatio ...... noid synthesis and cell growth
@en
P2093
J L Goldstein
P304
P407
P577
1980-07-01T00:00:00Z