Unexpected failure rates for modular assembly of engineered zinc fingers - Wikidata - awgldk - TriplyDB

Unexpected failure rates for modular assembly of engineered zinc fingers

Unexpected failure rates for modular assembly of engineered zinc fingers

http://www.wikidata.org/entity/Q28278303

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Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes Genome-scale engineering for systems and synthetic biology Genome editing with modularly assembled zinc-finger nucleases Targeting DNA With Fingers and TALENs TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain Precision editing of large animal genomes De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks Progress and prospects: zinc-finger nucleases as gene therapy agents Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification Targeted chromosomal deletions in human cells using zinc finger nucleases High-frequency modification of plant genes using engineered zinc-finger nucleases Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges Origins of Programmable Nucleases for Genome Engineering From Gene Targeting to Genome Editing: Transgenic animals applications and beyond Designed nucleases for targeted genome editing Making designer mutants in model organisms Progress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseases Advanced technologies for genetically manipulating the silkworm Bombyx mori, a model Lepidopteran insect Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection Proprietary science, open science and the role of patent disclosure: the case of zinc-finger proteins Genome Engineering With Zinc-Finger Nucleases Structure based design of protein linkers for zinc finger nuclease.Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels.Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction Eukaryotic systems broaden the scope of synthetic biology.Zinc finger nucleases as tools to understand and treat human diseases.Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences.Specificity landscapes of DNA binding molecules elucidate biological function ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms.Rule-based design of synthetic transcription factors in eukaryotes.Recombination in the human Pseudoautosomal region PAR1.Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs.ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool.Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish.Zebrafish Genome Engineering Using the CRISPR-Cas9 System.

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P2860

Unexpected failure rates for modular assembly of engineered zinc fingers

http://www.wikidata.org/entity/Q28278303

description

2008 nî lūn-bûn

@nan

2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Unexpected failure rates for modular assembly of engineered zinc fingers

@ast

Unexpected failure rates for modular assembly of engineered zinc fingers

@en

Unexpected failure rates for modular assembly of engineered zinc fingers

@nl

type

label

Unexpected failure rates for modular assembly of engineered zinc fingers

@ast

Unexpected failure rates for modular assembly of engineered zinc fingers

@en

Unexpected failure rates for modular assembly of engineered zinc fingers

@nl

prefLabel

Unexpected failure rates for modular assembly of engineered zinc fingers

@ast

Unexpected failure rates for modular assembly of engineered zinc fingers

@en

Unexpected failure rates for modular assembly of engineered zinc fingers

@nl

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P2860

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P1433

P1476

Unexpected failure rates for modular assembly of engineered zinc fingers

@en

P2093

Cherie L Ramirez

http://www.w3.org/2001/XMLSchema#string

Daniel F Voytas

http://www.w3.org/2001/XMLSchema#string

David A Wright

http://www.w3.org/2001/XMLSchema#string

Felix Müller-Lerch

http://www.w3.org/2001/XMLSchema#string

Fengli Fu

http://www.w3.org/2001/XMLSchema#string

J Keith Joung

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Townsend

http://www.w3.org/2001/XMLSchema#string

Jeffry D Sander

http://www.w3.org/2001/XMLSchema#string

Jonathan E Foley

http://www.w3.org/2001/XMLSchema#string

Ronnie J Winfrey

http://www.w3.org/2001/XMLSchema#string

P2860

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

Gene targeting using zinc finger nucleases

Human zinc fingers as building blocks in the construction of artificial transcription factors.

Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins.

Validated zinc finger protein designs for all 16 GNN DNA triplet targets.

P2888

P304

374-5

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

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3011076

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P356

10.1038/NMETH0508-374

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P407

P433

5

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P478

5

http://www.w3.org/2001/XMLSchema#string

P577

2008-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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5406598

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1021094033

http://www.w3.org/2001/XMLSchema#string

P698

18446154

http://www.w3.org/2001/XMLSchema#string