Human zinc fingers as building blocks in the construction of artificial transcription factors.
about
Tunable and multifunctional eukaryotic transcription factors based on CRISPR/CasSwitching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologiesTherapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesRapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modificationTargeted chromosomal deletions in human cells using zinc finger nucleasesTargeted genome editing in human cells with zinc finger nucleases constructed via modular assemblyZinc Finger Tools: custom DNA-binding domains for transcription factors and nucleasesHighly specific zinc finger proteins obtained by directed domain shuffling and cell-based selectionSuppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels.Chemically synthesized zinc finger molecules as nano-addressable probes for double-stranded DNAsGenome-editing Technologies for Gene and Cell TherapyDesigned nucleases for targeted genome editingThe prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disordersUnexpected failure rates for modular assembly of engineered zinc fingersDirected evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleasesInduction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor libraryProprietary science, open science and the role of patent disclosure: the case of zinc-finger proteinsMax-E47, a designed minimalist protein that targets the E-box DNA site in vivo and in vitro.Toward a functional annotation of the human genome using artificial transcription factorsPhenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors.Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library.Phenotypic alteration and target gene identification using combinatorial libraries of zinc finger proteins in prokaryotic cells.Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool.Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based methodTailor-made zinc-finger transcription factors activate FLO11 gene expression with phenotypic consequences in the yeast Saccharomyces cerevisiae.Design of a zinc finger protein binding a sequence upstream of the A20 gene.Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coliRapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arraysOptimization of minimum set of protein-DNA interactions: a quasi exact solution with minimum over-fittingPredicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences.Engineering butanol-tolerance in escherichia coli with artificial transcription factor libraries.p53 Gene repair with zinc finger nucleases optimised by yeast 1-hybrid and validated by Solexa sequencing.ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool.Mouse genetics: catalogue and scissorsControlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.Rescue the failed half-ZFN by a sensitive mammalian cell-based luciferase reporter systemHighly active zinc-finger nucleases by extended modular assemblyGlobal analysis of Drosophila Cys₂-His₂ zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants.Targeting artificial transcription factors to the utrophin A promoter: effects on dystrophic pathology and muscle function.
P2860
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P2860
Human zinc fingers as building blocks in the construction of artificial transcription factors.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Human zinc fingers as building ...... ificial transcription factors.
@ast
Human zinc fingers as building ...... ificial transcription factors.
@en
type
label
Human zinc fingers as building ...... ificial transcription factors.
@ast
Human zinc fingers as building ...... ificial transcription factors.
@en
prefLabel
Human zinc fingers as building ...... ificial transcription factors.
@ast
Human zinc fingers as building ...... ificial transcription factors.
@en
P2093
P2860
P356
P1433
P1476
Human zinc fingers as building ...... tificial transcription factors
@en
P2093
Byung-Il Yeh
Dong-Ki Lee
Eun-Hyun Ryu
Heung Sun Kwon
Hyean-Woo Lee
Hyo-Young Yang
Hyun-Chul Shin
Hyun-Won Kim
Jin-Soo Kim
Jinwoo Park
P2860
P2888
P304
P356
10.1038/NBT796
P50
P577
2003-02-18T00:00:00Z