Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas - Wikidata - awgldk - TriplyDB

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

http://www.wikidata.org/entity/Q28279024

about

Dcas supports cell polarization and cell-cell adhesion complexes in development Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteins CMS: an adapter molecule involved in cytoskeletal rearrangements BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells MICAL, a novel CasL interacting molecule, associates with vimentin p130Cas mediates the transforming properties of the anaplastic lymphoma kinase R-Ras promotes focal adhesion formation through focal adhesion kinase and p130(Cas) by a novel mechanism that differs from integrins.Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy CAS proteins in normal and pathological cell growth control Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.NEDD9 promotes oncogenic signaling in mammary tumor development.The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling P130Cas Src-binding and substrate domains have distinct roles in sustaining focal adhesion disassembly and promoting cell migration Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate Cytoskeleton-dependent tyrosine phosphorylation of the p130(Cas) family member HEF1 downstream of the G protein-coupled calcitonin receptor. Calcitonin induces the association of HEF1, paxillin, and focal adhesion kinase Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry CIZ, a zinc finger protein that interacts with p130(cas) and activates the expression of matrix metalloproteinases Domain-specific function of ShcC docking protein in neuroblastoma cells NEDD9 crucially regulates TGF-β-triggered epithelial-mesenchymal transition and cell invasion in prostate cancer cells: involvement in cancer progressiveness Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle The serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundle CAS proteins in health and disease: an update Cas and NEDD9 Contribute to Tumor Progression through Dynamic Regulation of the Cytoskeleton.NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes Restricted inactivation of serum response factor to the cardiovascular system Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate p130Cas, Crk-associated substrate plays essential roles in liver development by regulating sinusoidal endothelial cell fenestration Pyk2/CAKbeta tyrosine kinase activity-mediated angiogenesis of pulmonary vascular endothelial cells The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.Focal adhesion kinase: in command and control of cell motility FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly A pre-metazoan origin of the CRK gene family and co-opted signaling network Identification of Novel Crk-associated Substrate (p130Cas) Variants with Functionally Distinct Focal Adhesion Kinase Binding Activities Essential roles of Crk and CrkL in fibroblast structure and motility.C3G overexpression promotes the survival of rat-derived H9C2 cardiomyocytes by p-ERK1/2.

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P2860

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

http://www.wikidata.org/entity/Q28279024

description

1998 nî lūn-bûn

@nan

1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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1998 թվականի օգոստոսին հրատարակված գիտական հոդված

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Aparato circulatorio