Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene - Wikidata - awgldk - TriplyDB

Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene

Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene

http://www.wikidata.org/entity/Q28280248

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Early-onset Alzheimer's disease: nonamnestic subtypes and type 2 AD Etiologies of epilepsy: a comprehensive review Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1 Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model.Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease Genetics Underlying Atypical Parkinsonism and Related Neurodegenerative Disorders Common factors among Alzheimer's disease, Parkinson's disease, and epilepsy: possible role of the noradrenergic nervous system Need for a paradigm shift in therapeutic approaches to CNS injury Systematic review and meta-analysis of Japanese familial Alzheimer's disease and FTDP-17 Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).Novel PSEN1 G209A mutation in early-onset Alzheimer dementia supported by structural prediction.Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments.Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.Seizures in Alzheimer disease: clinical and epidemiological data.The presenilin 1 P264L mutation presenting as non-fluent/agrammatic primary progressive aphasia.Epilepsy and cognitive impairments in Alzheimer disease Clinical genetics of Alzheimer's disease Seizures and epilepsy in Alzheimer's disease Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism.Chemical Biology, Molecular Mechanism and Clinical Perspective of γ-Secretase Modulators in Alzheimer's Disease Identification of the PS1 Thr147Ile Variant in a Family with Very Early Onset Dementia and Expressive Aphasia.Comparison of clinical characteristics between familial and non-familial early onset Alzheimer's disease.Label-free quantitative LC-MS proteomics of Alzheimer's disease and normally aged human brains.Advances in the pathogenesis of Alzheimer's disease: a re-evaluation of amyloid cascade hypothesis.Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome.Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations Genetic aspects of Alzheimer disease Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer's disease mutations.Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.Familial Alzheimer's disease mutations in presenilins: effects on endoplasmic reticulum calcium homeostasis and correlation with clinical phenotypes.Molecular genetics of Alzheimer's disease: an update.BACE1 regulates voltage-gated sodium channels and neuronal activity.Shared cognitive and behavioral impairments in epilepsy and Alzheimer's disease and potential underlying mechanisms.Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.Amyloid-beta immunotherapy: the hope for Alzheimer disease?Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer's Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade.Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease.Correlating familial Alzheimer's disease gene mutations with clinical phenotype.

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P2860

Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene

http://www.wikidata.org/entity/Q28280248

description

2006 nî lūn-bûn

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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2006 թվականի փետրվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

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S00415-005-0019-5

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Journal of Neurology

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Clinical phenotypic heterogene ...... tions of the presenilin-1 gene

@en

P2093

A J Larner

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M Doran

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P2860

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop.

Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes.

Amyloid angiopathy and variability in amyloid beta deposition is determined by mutation position in presenilin-1-linked Alzheimer's disease.

Modulating processes within the central nervous system is central to therapeutic control of multiple sclerosis.

Screening for PS1 mutations in a referral-based series of AD cases: 21 novel mutations.

Variant Alzheimer disease with spastic paraparesis: neuropathological phenotype.

Cotton wool plaques in non-familial late-onset Alzheimer disease.

Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures.

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10.1007/S00415-005-0019-5

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2

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P921

Alzheimer's disease