Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2. - Wikidata - awgldk - TriplyDB

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

http://www.wikidata.org/entity/Q30493972

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Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model.Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks Genes associated with Alzheimer's disease: an overview and current status Emerging Link between Alzheimer's Disease and Homeostatic Synaptic Plasticity The genetic landscape of Alzheimer disease: clinical implications and perspectives Mutations in presenilin 2 and its implications in Alzheimer's disease and other dementia-associated disorders The genetics and neuropathology of Alzheimer's disease Common factors among Alzheimer's disease, Parkinson's disease, and epilepsy: possible role of the noradrenergic nervous system Probable novel PSEN2 Val214Leu mutation in Alzheimer's disease supported by structural prediction Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families Seizures in Alzheimer disease: clinical and epidemiological data.Clinical genetics of Alzheimer's disease Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release Assessing the contribution family data can make to case-control studies of rare variants.Seizures and epilepsy in Alzheimer's disease Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.Presenilin 2 influences miR146 level and activity in microglia.Early onset of hypersynchronous network activity and expression of a marker of chronic seizures in the Tg2576 mouse model of Alzheimer's disease.New approaches to genetic counseling and testing for Alzheimer's disease and frontotemporal degeneration Upregulated function of mitochondria-associated ER membranes in Alzheimer disease Imaging brain amyloid in nondemented young adults with Down syndrome using Pittsburgh compound B.Genetic Association between Presenilin 2 Polymorphisms and Alzheimer's Disease and Dementia of Lewy Body Type in a Japanese Population.Seizure-Induced Regulations of Amyloid-β, STEP61, and STEP61 Substrates Involved in Hippocampal Synaptic Plasticity.Genetic influences on atrophy patterns in familial Alzheimer's disease: a comparison of APP and PSEN1 mutations.Distinct subcellular patterns of neprilysin protein and activity in the brains of Alzheimer's disease patients, transgenic mice and cultured human neuronal cells.MicroRNAs mediating CNS inflammation: Small regulators with powerful potential.PSEN1 L226F mutation in a patient with early-onset Alzheimer's disease in Korea.New genes and new insights from old genes: update on Alzheimer disease.Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.Amyloid-beta immunotherapy: the hope for Alzheimer disease?Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer's Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade.Should EOAD patients be included in clinical trials?Position paper of the Italian Society for the study of Dementias (SINDEM) on the proposal of a new lexicon on Alzheimer disease.Genetics of dementia: update and guidelines for the clinician.Potential Similarities in Temporal Lobe Epilepsy and Alzheimer’s Disease: From Clinic to Pathology.Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis.Alzheimer's disease genetics: from the bench to the clinic.Targeting MicroRNAs in Prevention and Treatment of Neurodegenerative Disorders.Treatment of epilepsy in patients with Alzheimer's disease.

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P2860

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

http://www.wikidata.org/entity/Q30493972

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2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

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Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

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type

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Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

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Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

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prefLabel

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

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Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

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Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.

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P2093

Cheng-En Yu

http://www.w3.org/2001/XMLSchema#string

Ellen Steinbart

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Justin Stahl

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Thomas D Bird

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P2860

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease

Neuropathological stageing of Alzheimer-related changes

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

Presenilin mutations in Alzheimer's disease

Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

Presenilin-1 and intracellular calcium stores regulate neuronal glutamate uptake

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10.1093/BRAIN/AWQ033

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Pt 4

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133

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William E. Klunk

James B Leverenz

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2010-04-01T00:00:00Z

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43073104

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20375137

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Alzheimer's disease

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2850581

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