The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo
about
Wnt4 participates in the formation of vertebrate neuromuscular junctionSyne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junctionIdentification of a Dutch founder mutation in MUSK causing fetal akinesia deformation sequenceLarge-scale screening for novel low-affinity extracellular protein interactionsTo build a synapse: signaling pathways in neuromuscular junction assemblyAbnormal development of the neuromuscular junction in Nedd4-deficient miceMutations in the embryonal subunit of the acetylcholine receptor (CHRNG) cause lethal and Escobar variants of multiple pterygium syndromeMuSK is required for anchoring acetylcholinesterase at the neuromuscular junctionDistinct domains of MuSK mediate its abilities to induce and to associate with postsynaptic specializationsAbsence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophinPathogenesis of myasthenia gravis: update on disease types, models, and mechanismsNeuromuscular Junctions as Key Contributors and Therapeutic Targets in Spinal Muscular AtrophyThe Wnt and BMP families of signaling morphogens at the vertebrate neuromuscular junctionThe role of muscle-specific tyrosine kinase (MuSK) and mystery of MuSK myasthenia gravisCrosstalk between Agrin and Wnt signaling pathways in development of vertebrate neuromuscular junctionAblation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal deathGlutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubesNovel mouse model reveals distinct activity-dependent and -independent contributions to synapse developmentCrystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSKStructural basis of agrin-LRP4-MuSK signalingThe role of agrin in synaptic development, plasticity and signaling in the central nervous systemReceptor tyrosine kinase signaling: regulating neural crest development one phosphate at a timeRor2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate developmentDifferential targeting of components of the dystrophin complex to the postsynaptic membraneAnti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravisReduced glycosaminoglycan sulfation diminishes the agrin signal transduction pathwayFlt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in miceLrp4 is a receptor for Agrin and forms a complex with MuSKAgrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK)Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinaseAberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null miceLrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapsesLRP4 serves as a coreceptor of agrinGA-binding protein is dispensable for neuromuscular synapse formation and synapse-specific gene expressionCD24 is expressed by myofiber synaptic nuclei and regulates synaptic transmission.Agrin and synaptic laminin are required to maintain adult neuromuscular junctionsRegulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junctionCrystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSKIdentification of developmentally regulated expression of MuSK in astrocytes of the rodent retinaRapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptor
P2860
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P2860
The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The receptor tyrosine kinase M ...... lar junction formation in vivo
@ast
The receptor tyrosine kinase M ...... lar junction formation in vivo
@en
The receptor tyrosine kinase M ...... lar junction formation in vivo
@nl
type
label
The receptor tyrosine kinase M ...... lar junction formation in vivo
@ast
The receptor tyrosine kinase M ...... lar junction formation in vivo
@en
The receptor tyrosine kinase M ...... lar junction formation in vivo
@nl
prefLabel
The receptor tyrosine kinase M ...... lar junction formation in vivo
@ast
The receptor tyrosine kinase M ...... lar junction formation in vivo
@en
The receptor tyrosine kinase M ...... lar junction formation in vivo
@nl
P2093
P3181
P1433
P1476
The receptor tyrosine kinase M ...... lar junction formation in vivo
@en
P2093
D L Compton
D M Valenzuela
G D Yancopoulos
M V Simmons
P S DiStefano
P304
P3181
P356
10.1016/S0092-8674(00)81251-9
P407
P577
1996-05-17T00:00:00Z