Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK
about
Cell signaling by receptor tyrosine kinasesCrosstalk between Agrin and Wnt signaling pathways in development of vertebrate neuromuscular junctionStructural and Functional Analysis of Slit and Heparin Binding to Immunoglobulin-like Domains 1 and 2 of Drosophila RoboCrystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSKDirect contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signalingLrp4 is a receptor for Agrin and forms a complex with MuSKAgrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK)Altered active zones, vesicle pools, nerve terminal conductivity, and morphology during experimental MuSK myasthenia gravisCollagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling.Receptor tyrosine kinases: mechanisms of activation and signaling.MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.Structure and activation of MuSK, a receptor tyrosine kinase central to neuromuscular junction formation.Structural mechanisms of the agrin-LRP4-MuSK signaling pathway in neuromuscular junction differentiation.Structure of the neuromuscular junction: function and cooperative mechanisms in the synapse.The role of MuSK in synapse formation and neuromuscular disease.Pathogenic immune mechanisms at the neuromuscular synapse: the role of specific antibody-binding epitopes in myasthenia gravis.Synaptic Homeostasis and Its Immunological Disturbance in Neuromuscular Junction Disorders.Salbutamol-responsive limb-girdle congenital myasthenic syndrome due to a novel missense mutation and heteroallelic deletion in MUSK.Thermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain.Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution.Animal models of antimuscle-specific kinase myasthenia.The quaternary structure of amalgam, a Drosophila neuronal adhesion protein, explains its dual adhesion properties.A severe congenital myasthenic syndrome with "dropped head" caused by novel MUSK mutations.
P2860
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P2860
Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK
description
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
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im September 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2006/12/01)
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vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/12/01)
@nl
наукова стаття, опублікована в грудні 2006
@uk
مقالة علمية (نشرت في ديسمبر 2006)
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name
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
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Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@en
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@nl
type
label
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@ast
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@en
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@nl
prefLabel
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@ast
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@en
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@nl
P2860
P1476
Crystal structure of the agrin ...... receptor tyrosine kinase MuSK
@en
P2093
Amy L Stiegler
Steven J Burden
P2860
P304
P356
10.1016/J.JMB.2006.09.019
P407
P577
2006-09-12T00:00:00Z