HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells - Wikidata - awgldk - TriplyDB

HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

http://www.wikidata.org/entity/Q28281874

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NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation Dcas supports cell polarization and cell-cell adhesion complexes in development NEDD9 is a positive regulator of epithelial-mesenchymal transition and promotes invasion in aggressive breast cancer NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration CAS proteins in normal and pathological cell growth control HEF1-dependent Aurora A activation induces disassembly of the primary cilium NEDD9 promotes oncogenic signaling in mammary tumor development.A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9 c-Src and neural Wiskott-Aldrich syndrome protein (N-WASP) promote low oxygen-induced accelerated brain invasion by gliomas Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases NEDD9 crucially regulates TGF-β-triggered epithelial-mesenchymal transition and cell invasion in prostate cancer cells: involvement in cancer progressiveness Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle Overexpression of Nedd9 is a prognostic marker of human gastric cancer High expression of NEDD9 predicts adverse outcomes of colorectal cancer patients A novel Cas family member, HEPL, regulates FAK and cell spreading.NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells Expression of NEDD9 in pancreatic ductal adenocarcinoma and its clinical significance Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks NEDD9 promotes lung cancer metastasis through epithelial-mesenchymal transition NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner.The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis ZNF-mediated resistance to imatinib mesylate in gastrointestinal stromal tumor Identification and functional validation of CDH11, PCSK6 and SH3GL3 as novel glioma invasion-associated candidate genes.Multiple actions of lysophosphatidic acid on fibroblasts revealed by transcriptional profiling Therapeutic strategies for inhibiting invasion in glioblastoma.The retinoic acid inducible Cas-family signaling protein Nedd9 regulates neural crest cell migration by modulating adhesion and actin dynamics Cell migration and metastasis markers as targets of environmental pollutants and the Aryl hydrocarbon receptor.Identification of genes with allelic imbalance on 6p associated with nasopharyngeal carcinoma in southern Chinese Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin.Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.The pathobiology of glioma tumors High expression of HEF1 is associated with poor prognosis in urinary bladder carcinoma.Mesenchymal migration as a therapeutic target in glioblastoma.The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation.Src kinase determines the dynamic exchange of the docking protein NEDD9 (neural precursor cell expressed developmentally down-regulated gene 9) at focal adhesions.

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P2860

HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

http://www.wikidata.org/entity/Q28281874

description

2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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HEF1 is a necessary and specif ...... igration of glioblastoma cells

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HEF1 is a necessary and specif ...... igration of glioblastoma cells

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HEF1 is a necessary and specif ...... igration of glioblastoma cells

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HEF1 is a necessary and specif ...... igration of glioblastoma cells

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HEF1 is a necessary and specif ...... igration of glioblastoma cells

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HEF1 is a necessary and specif ...... igration of glioblastoma cells

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prefLabel

HEF1 is a necessary and specif ...... igration of glioblastoma cells

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HEF1 is a necessary and specif ...... igration of glioblastoma cells

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C L Gladson

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K Alexandropoulos

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W Wang

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1031961729

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