The HIV nef protein associates with protein kinase C theta
about
Direct interaction in T-cells between thetaPKC and the tyrosine kinase p59fynMechanism for down-regulation of CD28 by Nef.Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef proteinMyristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivoActivation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complexThe Nef protein of HIV-1 associates with rafts and primes T cells for activationBorna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling.PKC-Theta in Regulatory and Effector T-cell FunctionsCaspase-3-mediated cleavage of protein kinase C theta in induction of apoptosisA protein kinase Cdelta-binding protein SRBC whose expression is induced by serum starvationThe pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.Activation of NFAT-dependent gene expression by Nef: conservation among divergent Nef alleles, dependence on SH3 binding and membrane association, and cooperation with protein kinase C-thetaZeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle.The therapeutic potential of adenosine triphosphate as an immune modulator in the treatment of HIV/AIDS: a combination approach with HAART.Immune selection in vitro reveals human immunodeficiency virus type 1 Nef sequence motifs important for its immune evasion function in vivo.14-3-3s are potential biomarkers for HIV-related neurodegeneration.Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus.Inhibition of Kaposi's sarcoma-associated herpesvirus lytic replication by HIV-1 Nef and cellular microRNA hsa-miR-1258.The T-cell receptor zeta chain contains two homologous domains with which simian immunodeficiency virus Nef interacts and mediates down-modulation.The NTPase/helicase domain of hepatitis C virus nonstructural protein 3 inhibits protein kinase C independently of its NTPase activity.Mutational analysis of human immunodeficiency virus type 1 (HIV-1) accessory genes: requirement of a site in the nef gene for HIV-1 replication in activated CD4+ T cells in vitro and in vivo.Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway.Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes.Simultaneous assessment of CD4 and MHC-I downregulation by Nef primary isolates in the context of infection.Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice.Activation of the T-cell receptor signaling pathway by Nef from an aggressive strain of simian immunodeficiency virus.Mechanisms of HIV receptor and co-receptor down-regulation by prostratin: role of conventional and novel PKC isoforms.Down-modulation of TCR/CD3 surface complexes after HIV-1 infection is associated with differential expression of the viral regulatory genes.T-Cell Signaling in HIV-1 Infection.PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors.Impaired protein kinase C activation/translocation in Epstein-Barr virus-infected monocytes.Uncoupling activation-induced modulation of CD16 and CD69 in CD56+ cells during AIDS.Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction.Protein Kinase C-mediated Phosphorylation of HIV-I Nef in Human Cell Lines
P2860
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P2860
The HIV nef protein associates with protein kinase C theta
description
1996 nî lūn-bûn
@nan
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The HIV nef protein associates with protein kinase C theta
@ast
The HIV nef protein associates with protein kinase C theta
@en
The HIV nef protein associates with protein kinase C theta
@nl
type
label
The HIV nef protein associates with protein kinase C theta
@ast
The HIV nef protein associates with protein kinase C theta
@en
The HIV nef protein associates with protein kinase C theta
@nl
prefLabel
The HIV nef protein associates with protein kinase C theta
@ast
The HIV nef protein associates with protein kinase C theta
@en
The HIV nef protein associates with protein kinase C theta
@nl
P2093
P2860
P356
P1476
The HIV nef protein associates with protein kinase C theta
@en
P2093
B W Krushelnycky
D Mochly-Rosen
P2860
P304
P356
10.1074/JBC.271.28.16753
P407
P577
1996-07-12T00:00:00Z