PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase - Wikidata - awgldk - TriplyDB

PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase

PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase

http://www.wikidata.org/entity/Q28282194

about

PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21 A high efficiency strategy for binding property characterization of peptide-binding domains.Shared TP53 gene mutation in morphologically and phenotypically distinct concurrent primary small cell neuroendocrine carcinoma and adenocarcinoma of the prostate.Gene profiling suggests a common evolution of bladder cancer subtypes Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients.Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling T-LAK cell-originated protein kinase (TOPK) phosphorylation of Prx1 at Ser-32 prevents UVB-induced apoptosis in RPMI7951 melanoma cells through the regulation of Prx1 peroxidase activity.A porcine gene, PBK, differentially expressed in the longissimus muscle from Meishan and Large White pig.Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo p38 Mitogen-Activated Protein Kinase Pathway Regulates Genes during Proliferation and Differentiation in Oligodendrocytes Gene expression profiling distinguishes proneural glioma stem cells from mesenchymal glioma stem cells.Combined expressional analysis, bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders.Human tau expression reduces adult neurogenesis in a mouse model of tauopathy Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma.Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma.An essential role for p38 MAPK in cerebellar granule neuron precursor proliferation.Stable interference of EWS-FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target.Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.Lithium protects against glucocorticoid induced neural progenitor cell apoptosis in the developing cerebellum.Radiation-inducible miR-770-5p sensitizes tumors to radiation through direct targeting of PDZ-binding kinase.PDZ binding kinase, regulated by FoxM1, enhances malignant phenotype via activation of β-Catenin signaling in hepatocellular carcinoma.T-LAK cell-originated protein kinase is essential for the proliferation of hepatocellular carcinoma SMMC-7721 cells.Aldh1L1 is expressed by postnatal neural stem cells in vivo.Modulation of innate immune-related pathways in nicotine-treated SH-SY5Y cells The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network Molecular stages of rapid and uniform neuralization of human embryonic stem cells.PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response.A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation Activation of T-LAK-cell-originated protein kinase-mediated antioxidation protects against focal cerebral ischemia-reperfusion injury.PBK/TOPK expression in non-small-cell lung cancer: its correlation and prognostic significance with Ki67 and p53 expression.Impact of a novel biomarker, T-LAK cell-originating protein kinase (TOPK) expression on outcome in malignant glioma.Dexmedetomidine protects against glucocorticoid induced progenitor cell apoptosis in neonatal mouse cerebellum.Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus.Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice.In silico structural and functional analysis of the human TOPK protein by structure modeling and molecular dynamics studies.TOPK Promotes Microglia/Macrophage Polarization towards M2 Phenotype via Inhibition of HDAC1 and HDAC2 Activity after Transient Cerebral Ischemia.

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P2860

PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase

http://www.wikidata.org/entity/Q28282194

description

2005 nî lūn-bûn

@nan

2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

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2005年论文

@wuu

name

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

@ast

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

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PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

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type

label

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

@ast

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

@en

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

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prefLabel

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

@ast

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

@en

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

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P356

JNEUROSCI.3207-05.2005

P1433

Journal of Neuroscience

P1476

PBK/TOPK, a proliferating neur ...... ctivated protein kinase kinase

@en

P2093

A D R Garcia

http://www.w3.org/2001/XMLSchema#string

B Norris

http://www.w3.org/2001/XMLSchema#string

D H Geschwind

http://www.w3.org/2001/XMLSchema#string

E M Wexler

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H I Kornblum

http://www.w3.org/2001/XMLSchema#string

I Nakano

http://www.w3.org/2001/XMLSchema#string

J D Dougherty

http://www.w3.org/2001/XMLSchema#string

M V Sofroniew

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R Polakiewicz

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10773-10785

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scholarly article

P356

10.1523/JNEUROSCI.3207-05.2005

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P407

P433

46

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P478

25

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P50

Mark Livingstone

P577

2005-11-01T00:00:00Z

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16291951

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6725850

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