Impact of a novel biomarker, T-LAK cell-originating protein kinase (TOPK) expression on outcome in malignant glioma.

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Impact of a novel biomarker, T-LAK cell-originating protein kinase (TOPK) expression on outcome in malignant glioma.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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Impact of a novel biomarker, T ...... n outcome in malignant glioma.

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Impact of a novel biomarker, T ...... n outcome in malignant glioma.

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label

Impact of a novel biomarker, T ...... n outcome in malignant glioma.

@en

Impact of a novel biomarker, T ...... n outcome in malignant glioma.

@nl

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Impact of a novel biomarker, T ...... n outcome in malignant glioma.

@en

Impact of a novel biomarker, T ...... n outcome in malignant glioma.

@nl

P1476

Impact of a novel biomarker, T ...... on outcome in malignant glioma

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P2093

Daina Kashiwazaki

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Hideki Origasa

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Masaki Koh

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Michiya Sugimori

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Shoichi Nagai

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Takahiro Tomita

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Tomohide Hayashi

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Yumiko Hayakawa

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P2860

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins

Cloning and expression of a novel MAPKK-like protein kinase, lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cells

PBK/TOPK is a novel mitotic kinase which is upregulated in Burkitt's lymphoma and other highly proliferative malignant cells

PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase

Factors influencing survival in high-grade gliomas.

Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo

TOPK is highly expressed in circulating tumor cells, enabling metastasis of prostate cancer

Long-term survival in glioblastoma: methyl guanine methyl transferase (MGMT) promoter methylation as independent favourable prognostic factor.

PBK/TOPK enhances aggressive phenotype in prostate cancer via β-catenin-TCF/LEF-mediated matrix metalloproteinases production and invasion.

PBK/TOPK expression correlates with mutant p53 and affects patients' prognosis and cell proliferation and viability in lung adenocarcinoma.

P304

144-153

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scholarly article

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10.1111/NEUP.12446

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P478

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Satoshi Kuroda

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2017-12-21T00:00:00Z

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P698

29271010

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