Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over - Wikidata - awgldk - TriplyDB

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

http://www.wikidata.org/entity/Q28282791

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ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes Estimating cell depth from somatic mutations MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability Factors affecting levels of genetic diversity in natural populations Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6 HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes.Rates of spontaneous mutation Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks DNA mismatch repair: molecular mechanism, cancer, and ageing Amplification of multiple genomic loci from single cells isolated by laser micro-dissection of tissues The origins and early evolution of DNA mismatch repair genes--multiple horizontal gene transfers and co-evolution Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesis Manipulation of DNA Repair Proficiency in Mouse Models of Colorectal Cancer Modeling the study of DNA damage responses in mice Meiotic pairing and segregation of achiasmate sex chromosomes in eutherian mammals: the role of SYCP3 protein Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males Muscle-bound primordial stem cells give rise to myofiber-associated myogenic and non-myogenic progenitors Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope.Comparing algorithms that reconstruct cell lineage trees utilizing information on microsatellite mutations The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse Cell lineage analysis of the mammalian female germline Colon stem cell and crypt dynamics exposed by cell lineage reconstruction Genetic analysis of genome-scale recombination rate evolution in house mice Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha.The MER3 DNA helicase catalyzes the unwinding of holliday junctions.Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.Impact of DNA mismatch repair system alterations on human fertility and related treatments Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility Variation in crossover frequencies perturb crossover assurance without affecting meiotic chromosome segregation in Saccharomyces cerevisiae Mechanisms and functions of DNA mismatch repair ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2 DNA replication error-induced extinction of diploid yeast The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions.Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair Down-regulation of DNA mismatch repair enhances initiation and growth of neuroblastoma and brain tumour multicellular spheroids

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

http://www.wikidata.org/entity/Q28282791

description

1996 nî lūn-bûn

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1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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1996 թվականի հուլիսին հրատարակված գիտական հոդված

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1996年の論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年论文

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name

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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type

label

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

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Nature Genetics

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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

@en

P2093

A Bradley

http://www.w3.org/2001/XMLSchema#string

A C Harris

http://www.w3.org/2001/XMLSchema#string

A W Plug

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C E Bronner

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C Monell

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D M Christie

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N Arnheim

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R M Liskay

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S M Baker

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T A Prolla

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P2860

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

MSH2 deficient mice are viable and susceptible to lymphoid tumours

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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336-42

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scholarly article

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667221

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10.1038/NG0796-336

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3

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13

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1996-07-01T00:00:00Z

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14528876

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8673133

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