Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
about
Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemiaProteolytic activation of ETK/Bmx tyrosine kinase by caspasesDifferential evolutionary wiring of the tyrosine kinase BtkEndothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesionTranscription factor STAT5A is a substrate of Bruton's tyrosine kinase in B cells.A novel reverse transduction adenoviral array for the functional analysis of shRNA librariesIbrutinib: a new frontier in the treatment of chronic lymphocytic leukemia by Bruton's tyrosine kinase inhibitionProtein kinases: emerging therapeutic targets in chronic lymphocytic leukemia.Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival.The effects of the Epstein-Barr virus latent membrane protein 2A on B cell function.Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cellsReceptor-guided 3D-QSAR studies, molecular dynamics simulation and free energy calculations of Btk kinase inhibitorsClinical potential of targeting Bruton's tyrosine kinase.Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity.PCI-32765: a novel Bruton's tyrosine kinase inhibitor for the treatment of lymphoid malignancies.Ibrutinib and novel BTK inhibitors in clinical development.Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.NF-kappaB regulates the transcription of protein tyrosine kinase Tec.ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation.Apoptosis induced by Na+/H+ antiport inhibition activates the LEI/L-DNase II pathway.Induction of erythroid differentiation by inhibition of Ras/ERK pathway in a friend murine leukemia cell line.Bruton's tyrosine kinase associates with the actin-based cytoskeleton in activated platelets.Bruton's tyrosine kinase is a substrate of calpain in human platelets.Defective expression of Bruton's tyrosine kinase in acute lymphoblastic leukemia.Bruton's tyrosine kinase phosphorylates cAMP-responsive element-binding protein at serine 133 during neuronal differentiation in immortalized hippocampal progenitor cells.Dual targeting of Bruton's tyrosine kinase and Janus kinase 3 with rationally designed inhibitors prevents graft-versus-host disease (GVHD) in a murine allogeneic bone marrow transplantation model.Role of the outward delayed rectifier K+ current in ceramide-induced caspase activation and apoptosis in cultured cortical neurons.Role of Bruton's tyrosine kinase in macrophage apoptosis.Molecular modeling studies on series of Btk inhibitors using docking, structure-based 3D-QSAR and molecular dynamics simulation: a combined approach.
P2860
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P2860
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@ast
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@en
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@nl
type
label
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@ast
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@en
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@nl
prefLabel
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@ast
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@en
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@nl
P3181
P1476
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
@en
P2093
P304
P3181
P356
10.1016/S0006-2952(98)00122-1
P407
P577
1998-09-15T00:00:00Z