Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

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Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

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Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

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Item

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Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

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Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

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Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

@en

Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

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P1476

Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.

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P2093

Anna Lucia Fallacara

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Chiara Greco

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Francesca Musumeci

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Ilaria Giacchello

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Monica Sanna

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Rosario Amato

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Silvia Schenone

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P2860

Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia

Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases

Potent and selective Bruton's tyrosine kinase inhibitors: discovery of GDC-0834

Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability

Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations

Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib

P304

1-14

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P31

scholarly article

P356

10.1080/13543776.2017.1355908

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P407

English

P577

2017-07-13T00:00:00Z

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P698

28705083

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