Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats
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Interactions between human glutamate carboxypeptidase II and urea-based inhibitors: structural characterizationStructural characterization of P1′-diversified urea-based inhibitors of glutamate carboxypeptidase IINAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammationNAAG peptidase inhibitors block cognitive deficit induced by MK-801 and motor activation induced by d-amphetamine in animal models of schizophrenia.Advances in understanding the peptide neurotransmitter NAAG and appearance of a new member of the NAAG neuropeptide familyGroup II mGluR agonist LY354740 and NAAG peptidase inhibitor effects on prepulse inhibition in PCP and D-amphetamine models of schizophrenia.Phencyclidine and dizocilpine induced behaviors reduced by N-acetylaspartylglutamate peptidase inhibition via metabotropic glutamate receptors.Pharmacokinetics and pharmacodynamics of the glutamate carboxypeptidase II inhibitor 2-MPPA show prolonged alleviation of neuropathic pain through an indirect mechanism.mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonistsSelective CNS Uptake of the GCP-II Inhibitor 2-PMPA following Intranasal Administration.Differences in glutamate receptors and inflammatory cell numbers are associated with the resolution of pain in human rotator cuff tendinopathyEffects of N-acetylaspartylglutamate (NAAG) peptidase inhibition on release of glutamate and dopamine in prefrontal cortex and nucleus accumbens in phencyclidine model of schizophreniaNAAG peptidase inhibitors and deletion of NAAG peptidase gene enhance memory in novel object recognition test.Metabotropic glutamate receptors as targets for analgesia: antagonism, activation, and allosteric modulation.Glutamate carboxypeptidase II in diagnosis and treatment of neurologic disorders and prostate cancerNAAG, NMDA receptor and psychosisSmall-molecule PSMA ligands. Current state, SAR and perspectives.The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological diseaseN-acetylaspartylglutamate is an agonist at mGluR₃ in vivo and in vitro.Nociception modulation by supraspinal group III metabotropic glutamate receptors.NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer's, and Ethanol Intoxication.N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors.Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies.Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model.Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain.Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis.Group II Metabotropic Glutamate Receptors: Role in Pain Mechanisms and Pain Modulation
P2860
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P2860
Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Local administration of N-acet ...... sic in peripheral pain in rats
@ast
Local administration of N-acet ...... sic in peripheral pain in rats
@en
Local administration of N-acet ...... sic in peripheral pain in rats
@nl
type
label
Local administration of N-acet ...... sic in peripheral pain in rats
@ast
Local administration of N-acet ...... sic in peripheral pain in rats
@en
Local administration of N-acet ...... sic in peripheral pain in rats
@nl
prefLabel
Local administration of N-acet ...... sic in peripheral pain in rats
@ast
Local administration of N-acet ...... sic in peripheral pain in rats
@en
Local administration of N-acet ...... sic in peripheral pain in rats
@nl
P2093
P1476
Local administration of N-acet ...... sic in peripheral pain in rats
@en
P2093
Alan Kozikowski
Alessandra Bartolozzi
Barbara Wroblewska
Jayaprakash Sarva
Joseph H Neale
Osamu Saito
Tatsuo Yamamoto
Tomasz Bzdega
Tomohiko Aoe
P304
P356
10.1111/J.1460-9568.2006.05272.X
P407
P577
2007-01-01T00:00:00Z