Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases
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Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activationEngagement of Gab1 and Gab2 in erythropoietin signalingErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinasesBox 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated stimulation of mitogen-activated protein kinase. Evidence for participation of multiple signaling pathways which converge at RasErythropoietin induces the tyrosine phosphorylation of insulin receptor substrate-2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activationGrowth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signalingJanus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferonsA new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes.A crowd-sourcing approach for the construction of species-specific cell signaling networks.Murine leukemias with retroviral insertions at Lmo2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy.STAT6-deficient mice exhibit normal induction of murine AIDS and expression of immunoglobulin E following infection with LP-BM5 murine leukemia virusesInhibition of tumor growth by NK1.1+ cells and CD8+ T cells activated by IL-15 through receptor beta/common gamma signaling in trans.The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes.Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cellsThe extracellular and transmembrane domains of the γC and interleukin (IL)-13 receptor α1 chains, not their cytoplasmic domains, dictate the nature of signaling responses to IL-4 and IL-13.Cellular effects of phosphotyrosine-binding domain inhibitors on insulin receptor signaling and trafficking.Convergence and divergence of the signaling pathways for insulin and phosphoinositolglycans.IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2V617F-positive myeloproliferative neoplasms.Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages.Shared gamma(c) subunit within the human interleukin-7 receptor complex. A molecular basis for the pathogenesis of X-linked severe combined immunodeficiency.Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis.JAKs go nuclear: emerging role of nuclear JAK1 and JAK2 in gene expression and cell growth.Critical role of the membrane-proximal, proline-rich motif of the interleukin-2 receptor gammac chain in the Jak3-independent signal transduction.Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion.Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinaseInterleukin-4 up-regulates mouse mammary tumor virus expression yet is not required for in vivo virus spread.Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons.Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway.Role of tyrosine kinases in induction of the c-jun proto-oncogene in irradiated B-lineage lymphoid cells.Type 3 Diabetes: Cross Talk between Differentially Regulated Proteins of Type 2 Diabetes Mellitus and Alzheimer's Disease.Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules.Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells.The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.Signal transduction by interleukin-12 and interleukin-2. A comparison and contrast.Regulation of gene expression, growth, and cell survival by IL-4: contribution of multiple signaling pathways.The MicroRNA miR-191 Supports T Cell Survival Following Common γ Chain SignalingThe insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.Signalling pathways of an insulin-mimetic phosphoinositolglycan-peptide in muscle and adipose tissue.Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.
P2860
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P2860
Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@ast
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@en
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@nl
type
label
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@ast
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@en
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@nl
prefLabel
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@ast
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@en
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@nl
P2093
P3181
P356
P1476
Interleukins 2, 4, 7, and 15 s ...... Potential role of JAK kinases
@en
P2093
E P Hanson
J A Johnston
J H Pierce
J J O'Shea
P304
P3181
P356
10.1074/JBC.270.48.28527
P407
P577
1995-12-01T00:00:00Z