High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
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Expressional patterns of chaperones in ten human tumor cell lines.Paralog Specific Hsp90 Inhibitors - A Brief History and a Bright FutureFunctions of the Hsp90 chaperone system: lifting client proteins to new heightsPlasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in MiceThe human Cdc37.Hsp90 complex studied by heteronuclear NMR spectroscopyFunctional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasivenessGeldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (hsp60)Regulation and function of the human HSP90AA1 geneHeat shock protein 90 inhibition: rationale and clinical potential.Heat shock protein expression in canine malignant mammary tumours.To fold or not to fold: modulation and consequences of Hsp90 inhibition.BIIB021, an Hsp90 inhibitor, effectively kills a myelodysplastic syndrome cell line via the activation of caspases and inhibition of PI3K/Akt and NF-κB pathway proteins.Chaperones in cell cycle regulation and mitogenic signal transduction: a review.Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinicWithaferin A targets heat shock protein 90 in pancreatic cancer cells.Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy.A dynamic view of ATP-coupled functioning cycle of Hsp90 N-terminal domain.Targeting paediatric acute lymphoblastic leukaemia: novel therapies currently in developmentHeat shock proteins and acute leukemias.Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia.A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma.Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion KinaseNatural product inhibitors of Hsp90: potential leads for drug discoveryNovobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.Inhibition of heat shock protein 90 (HSP90) as a therapeutic strategy for the treatment of myeloma and other cancers.Acute regulation of PDK1 by a complex interplay of molecular switches.2-phenylethynesulphonamide (PFT-μ) enhances the anticancer effect of the novel hsp90 inhibitor NVP-AUY922 in melanoma, by reducing GSH levels.The stress response paradox: fighting degeneration at the cost of cancer.HSP90 inhibition results in apoptosis of Philadelphia acute lymphoblastic leukaemia cells: an attractive prospect of new targeted agents.Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.The expression of glucose regulated protein-94 in colorectal carcinoma cells treated by sodium butyrate.Heat shock factor 2 is associated with the occurrence of lung cancer by enhancing the expression of heat shock proteins.The Hsp90 chaperone complex A potential target for cancer therapy?Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives.Significance of heat-shock protein (HSP) 90 expression in acute myeloid leukemia cells.Expression of heat-shock protein 90 in glucocorticoid-sensitive and -resistant childhood acute lymphoblastic leukaemia.Regulation of glucocorticoid receptor steroid binding and trafficking by the hsp90/hsp70-based chaperone machinery: implications for clinical intervention.mRNA expression levels of (co)chaperone molecules of the glucocorticoid receptor are not involved in glucocorticoid resistance in pediatric ALL.The HSP90 inhibitor NVP-AUY922-AG inhibits the PI3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells.Traditional Chinese medicine as dual guardians against hypertension and cancer?
P2860
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P2860
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
description
1992 nî lūn-bûn
@nan
1992 թուականին հրատարակուած գիտական յօդուած
@hyw
1992 թվականին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@ast
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@en
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@nl
type
label
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@ast
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@en
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@nl
prefLabel
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@ast
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@en
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@nl
P2093
P1433
P1476
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
@en
P2093
P304
P356
10.1016/0145-2126(92)90008-U
P407
P577
1992-01-01T00:00:00Z