Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
about
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Yap1 acts downstream of α-catenin to control epidermal proliferationLigand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativityInteraction proteome of human Hippo signaling: modular control of the co-activator YAP1Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120Angiomotin is a novel Hippo pathway component that inhibits YAP oncoproteinThe hippo signaling pathway in development and cancerStructures of YAP protein domains reveal promising targets for development of new cancer drugsIdentification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 geneY65C missense mutation in the WW domain of the Golabi-Ito-Hall syndrome protein PQBP1 affects its binding activity and deregulates pre-mRNA splicingThe MST/Hippo Pathway and Cell Death: A Non-Canonical AffairThe Roles of NDR Protein Kinases in Hippo SignallingYAP-Mediated Mechanotransduction in Skeletal MuscleEmerging role of Hippo pathway in gastric and other gastrointestinal cancersSignaling in Fibrosis: TGF-β, WNT, and YAP/TAZ ConvergeMammalian Hippo signalling: a kinase network regulated by protein-protein interactionsThe two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatmentStructure of a 14-3-3σ–YAP phosphopeptide complex at 1.15 Å resolutionEmerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancerOpposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAPThe Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionMerlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survivalThe role of YAP transcription coactivator in regulating stem cell self-renewal and differentiationCooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exitMultiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix AdhesionReciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells.Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.Framework to function: mechanosensitive regulators of gene transcriptionThe essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesisLATS2 is de-methylated and overexpressed in nasopharyngeal carcinoma and predicts poor prognosis.Yes-associated protein (YAP) modulates oncogenic features and radiation sensitivity in endometrial cancerMammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A catalytic subunit levels and consequent suppression of inhibitory Raf-1 phosphorylationThe Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.Hippo pathway activity influences liver cell fate.ZO proteins redundantly regulate the transcription factor DbpA/ZONABNormal hematopoietic stem cell function in mice with enforced expression of the Hippo signaling effector YAP1Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells.Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.Willin, an upstream component of the hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblastsYAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets.
P2860
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P2860
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@ast
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@en
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@nl
type
label
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@ast
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@en
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@nl
prefLabel
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@ast
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@en
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@nl
P2093
P3181
P356
P1476
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
@en
P2093
Marius Sudol
Tsutomu Oka
Virginia Mazack
P304
P3181
P356
10.1074/JBC.M804380200
P407
P577
2008-10-10T00:00:00Z