Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1 - Wikidata - awgldk - TriplyDB

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

http://www.wikidata.org/entity/Q28287877

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ARF-dependent regulation of ATM and p53 associated KZNF (Apak) protein activity in response to oncogenic stress The E3 ligase Smurf1 regulates Wolfram syndrome protein stability at the endoplasmic reticulum CKIP-1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradation SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1 REGgamma proteasome mediates degradation of the ubiquitin ligase Smurf1 HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradation Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases Capping protein regulators fine-tune actin assembly dynamics Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity A Smad action turnover switch operated by WW domain readers of a phosphoserine code Smurf-mediated differential proteolysis generates dynamic BMP signaling in germline stem cells during Drosophila testis development.Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation A novel role of CKIP-1 in promoting megakaryocytic differentiation Association of CKIP-1 P21A polymorphism with risk of chronic heart failure in a Chinese population.Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy.FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.Pivotal role of the C2 domain of the Smurf1 ubiquitin ligase in substrate selection p53 degradation by a coronavirus papain-like protease suppresses type I interferon signaling.Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.Chitosan/siCkip-1 biofunctionalized titanium implant for improved osseointegration in the osteoporotic condition.Crystallization and preliminary X-ray crystallographic analysis of the human CKIP-1 pleckstrin homology domain Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration.Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration Smurf1 regulation of DAB2IP controls cell proliferation and migration Post-translational Regulation of Runx2 in Bone and Cartilage.Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging.Smurf control in bone cells.A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks.Crosstalk between kinases and Nedd4 family ubiquitin ligases.E3 ubiquitin ligases in regulating stress fiber, lamellipodium, and focal adhesion dynamics.CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα.CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation.Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.Development of nanomaterials for bone-targeted drug delivery.KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis.Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages.Selective compounds enhance osteoblastic activity by targeting HECT domain of ubiquitin ligase Smurf1.

P2860

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P2860

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

http://www.wikidata.org/entity/Q28287877

description

2008 nî lūn-bûn

@nan

2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@ast

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@en

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@nl

type

label

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@ast

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@en

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@nl

prefLabel

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@ast

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@en

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@nl

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P1433

Nature Cell Biology

P1476

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

@en

P2093

Fuchu He

http://www.w3.org/2001/XMLSchema#string

Guichun Xing

http://www.w3.org/2001/XMLSchema#string

Kefeng Lu

http://www.w3.org/2001/XMLSchema#string

Li Li

http://www.w3.org/2001/XMLSchema#string

Lingqiang Zhang

http://www.w3.org/2001/XMLSchema#string

Shenli Xi

http://www.w3.org/2001/XMLSchema#string

Tujun Weng

http://www.w3.org/2001/XMLSchema#string

Xiao Yang

http://www.w3.org/2001/XMLSchema#string

Xiushan Yin

http://www.w3.org/2001/XMLSchema#string

Xuan Cheng

http://www.w3.org/2001/XMLSchema#string

P2860

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein

Role for the pleckstrin homology domain-containing protein CKIP-1 in AP-1 regulation and apoptosis

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

P2888

P304

994-1002

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scholarly article

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5039790

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P356

10.1038/NCB1760

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P433

8

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10

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2008-08-01T00:00:00Z

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51415720

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1003579432

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18641638

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