Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition - Wikidata - awgldk - TriplyDB

Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition

Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition

http://www.wikidata.org/entity/Q28288824

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Spinal muscular atrophy The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy Histone deacetylase inhibitors as potential treatment for spinal muscular atrophy Spinal muscular atrophy: development and implementation of potential treatments SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice.Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides Translational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivo Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy.PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy.Protective effects of butyrate-based compounds on a mouse model for spinal muscular atrophy.Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice The effect of diet on the protective action of D156844 observed in spinal muscular atrophy mice.Trans-splicing-mediated improvement in a severe mouse model of spinal muscular atrophy.Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?Mouse survival motor neuron alleles that mimic SMN2 splicing and are inducible rescue embryonic lethality early in development but not late Spinal muscular atrophy: new and emerging insights from model mice The Smn-independent beneficial effects of trichostatin A on an intermediate mouse model of spinal muscular atrophy.Spinal muscular atrophy: mechanisms and therapeutic strategies.Motor unit abnormalities in Dystonia musculorum mice Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model Splicing of the Survival Motor Neuron genes and implications for treatment of SMA Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy.Temporal requirement for high SMN expression in SMA mice Therapeutic strategies for the treatment of spinal muscular atrophy.SMN-inducing compounds for the treatment of spinal muscular atrophy.Intramuscular scAAV9-SMN injection mediates widespread gene delivery to the spinal cord and decreases disease severity in SMA mice.Spinal Muscular Atrophy Therapeutics: Where do we Stand?Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy.Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds Increased IGF-1 in muscle modulates the phenotype of severe SMA mice Spinal muscular atrophy: from tissue specificity to therapeutic strategies Motor neuron cell-nonautonomous rescue of spinal muscular atrophy phenotypes in mild and severe transgenic mouse models Nutritional practices at a glance: spinal muscular atrophy type I nutrition survey findings.Glucose metabolism and pancreatic defects in spinal muscular atrophy Increasing expression and decreasing degradation of SMN ameliorate the spinal muscular atrophy phenotype in mice Vascular perfusion abnormalities in infants with spinal muscular atrophy.

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Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition

http://www.wikidata.org/entity/Q28288824

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2008 nî lūn-bûn

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2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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Sustained improvement of spina ...... trichostatin A plus nutrition

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Sustained improvement of spina ...... trichostatin A plus nutrition

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Annals of Neurology

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Sustained improvement of spina ...... trichostatin A plus nutrition

@en

P2093

Addis A Taye

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Barrington G Burnett

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Charlotte J Sumner

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Dong W Choe

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Heather L Narver

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Lingling Kong

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Marta Bosch-Marcé

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Michael A Eckhaus

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P2860

The changing natural history of spinal muscular atrophy type 1

Randomized, double-blind, placebo-controlled trial of phenylbutyrate in spinal muscular atrophy

Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy.

Identification and characterization of a spinal muscular atrophy-determining gene

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2.

Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy.

The survival motor neuron protein in spinal muscular atrophy.

Blood vessels and nerves: common signals, pathways and diseases.

Vessels and nerves: marching to the same tune.

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465-70

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scholarly article

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2022323

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10.1002/ANA.21449

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4

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64

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2008-10-01T00:00:00Z

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18661558

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spinal muscular atrophy