Length and protein kinase A modulations of myocytes in cardiac myosin binding protein C-deficient mice
about
Novel control of cardiac myofilament response to calcium by S-glutathionylation at specific sites of myosin binding protein CSupport for a trimeric collar of myosin binding protein C in cardiac and fast skeletal muscle, but not in slow skeletal muscleMyofilament Calcium Sensitivity: Role in Regulation of In vivo Cardiac Contraction and RelaxationHow do MYBPC3 mutations cause hypertrophic cardiomyopathy?The ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathyAdrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in miceIncreased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in miceProtein kinase D increases maximal Ca2+-activated tension of cardiomyocyte contraction by phosphorylation of cMyBP-C-Ser315Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutationsRepair of Mybpc3 mRNA by 5'-trans-splicing in a Mouse Model of Hypertrophic CardiomyopathyIn the thick of it: HCM-causing mutations in myosin binding proteins of the thick filamentLength-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylationEpigallocatechin-3-Gallate Accelerates Relaxation and Ca2+ Transient Decay and Desensitizes Myofilaments in Healthy and Mybpc3-Targeted Knock-in Cardiomyopathic Mice.How do hypertrophic cardiomyopathy mutations affect myocardial function in carriers with normal wall thickness? Assessment with cardiovascular magnetic resonance.Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distributionCalcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient miceImpact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue.Protein kinase A-induced myofilament desensitization to Ca(2+) as a result of phosphorylation of cardiac myosin-binding protein CFHL2 expression and variants in hypertrophic cardiomyopathy.Cardiac myosin binding protein C phosphorylation affects cross-bridge cycle's elementary steps in a site-specific manner.Length-dependent changes in contractile dynamics are blunted due to cardiac myosin binding protein-C ablation.Cardiac function is regulated by B56α-mediated targeting of protein phosphatase 2A (PP2A) to contractile relevant substrates.Diastolic myofilament dysfunction in the failing human heart.Magnitude of length-dependent changes in contractile properties varies with titin isoform in rat ventricles.Dissociation of structural and functional phenotypes in cardiac myosin-binding protein C conditional knockout mice.Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium.ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease.Myosin cross-bridge dynamics in patients with hypertension and concentric left ventricular remodeling.Cardiac Myosin-binding Protein C and Troponin-I Phosphorylation Independently Modulate Myofilament Length-dependent Activation.Cardiac Myosin Binding Protein-C Phosphorylation Modulates Myofilament Length-Dependent ActivationTitin strain contributes to the Frank-Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins.Cardiac Myosin-binding protein C modulates the tuning of the molecular motor in the heartSlowing of contractile kinetics by myosin-binding protein C can be explained by its cooperative binding to the thin filament.Calcium sensitivity and myofilament lattice structure in titin N2B KO mice.In vivo cardiac myosin binding protein C gene transfer rescues myofilament contractile dysfunction in cardiac myosin binding protein C null miceCardiac myosin binding protein-C phosphorylation in a {beta}-myosin heavy chain backgroundMultiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins.Designing heart performance by gene transfer.The cAMP binding protein Epac regulates cardiac myofilament function.Effects of contractile protein phosphorylation on force development in permeabilized rat cardiac myocytes.
P2860
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P2860
Length and protein kinase A modulations of myocytes in cardiac myosin binding protein C-deficient mice
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2006 nî lūn-bûn
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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Length and protein kinase A mo ...... nding protein C-deficient mice
@ast
Length and protein kinase A mo ...... nding protein C-deficient mice
@en
Length and protein kinase A mo ...... nding protein C-deficient mice
@nl
type
label
Length and protein kinase A mo ...... nding protein C-deficient mice
@ast
Length and protein kinase A mo ...... nding protein C-deficient mice
@en
Length and protein kinase A mo ...... nding protein C-deficient mice
@nl
prefLabel
Length and protein kinase A mo ...... nding protein C-deficient mice
@ast
Length and protein kinase A mo ...... nding protein C-deficient mice
@en
Length and protein kinase A mo ...... nding protein C-deficient mice
@nl
P2093
P1476
Length and protein kinase A mo ...... nding protein C-deficient mice
@en
P2093
Alain Lacampagne
Guillermo Salazar
Guy Vassort
Nicolas Vignier
Olivier Cazorla
Szabolcs Szilagyi
P304
P356
10.1016/J.CARDIORES.2005.11.009
P407
P577
2006-02-01T00:00:00Z