Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption
about
The HTLV-1 Tax interactomeDirect activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functionsOpposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cellsMixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complexThe net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shockMEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cellsMEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytesA comprehensive pathway map of epidermal growth factor receptor signalingModulating sensitivity to drug-induced apoptosis: the future for chemotherapy?A RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1MEKK1 binds raf-1 and the ERK2 cascade componentsAxin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activationLaminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathwaysWiring the cell signaling circuitry by the NF-kappa B and JNK1 crosstalk and its applications in human diseasesSpecific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitroQuinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosisTRAIL activates JNK and NF-κB through RIP1-dependent and -independent pathwaysApoptosis induced by cytoskeletal disruption requires distinct domains of MEKK1Epithelial sheet movement requires the cooperation of c-Jun and MAP3K1Subdomain VIII is a specificity-determining region in MEKK1Comprehensive logic based analyses of Toll-like receptor 4 signal transduction pathwayStress- and cell type-dependent regulation of transfected c-Jun N-terminal kinase and mitogen-activated protein kinase kinase isoformsPak1 as a novel therapeutic target for antihypertrophic treatment in the heartA role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closureDeciphering gene expression program of MAP3K1 in mouse eyelid morphogenesisGab1 is an integrator of cell death versus cell survival signals in oxidative stressDoxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsp115 Rho GTPase activating protein interacts with MEKK1.Mitogen-activated protein kinases: specific messages from ubiquitous messengersInteraction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease.MAP3K1 function is essential for cytoarchitecture of the mouse organ of Corti and survival of auditory hair cells.MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption.c-Jun N-terminal kinase activation in Xenopus laevis eggs and embryos. A possible non-genomic role for the JNK signaling pathway.Ste20-related proline/alanine-rich kinase (SPAK) regulated transcriptionally by hyperosmolarity is involved in intestinal barrier function.Large-scale evidence for conservation of NMD candidature across mammals.Excitotoxins in neuronal apoptosis and necrosis.Deltex regulates T-cell activation by targeted degradation of active MEKK1.Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.
P2860
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P2860
Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@ast
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@en
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@nl
type
label
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@ast
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@en
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@nl
prefLabel
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@ast
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@en
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@nl
P2093
P3181
P1433
P1476
Role of MEKK1 in cell survival ...... ed by targeted gene disruption
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.282.5395.1911
P407
P577
1998-12-04T00:00:00Z