Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
about
Selective inhibition of BET bromodomainsAmino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion proteinEvidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cellPML, a growth suppressor disrupted in acute promyelocytic leukemiaConjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus.Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteinsPLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptorsFrom an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemiaRetinoic acid and arsenic for treating acute promyelocytic leukemiaInhibition of histone deacetylases in cancer therapy: lessons from leukaemiaBladder Cancer Stem-Like Cells: Their Origin and Therapeutic PerspectivesMolecular landscape of acute myeloid leukemia in younger adults and its clinical relevanceThe function, regulation and therapeutic implications of the tumor suppressor protein, PMLThe Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia TherapyRole of Retinoic Acid-Metabolizing Cytochrome P450s, CYP26, in Inflammation and CancerAcute promyelocytic leukemia: where did we start, where are we now, and the futureSheep, wolf, or werewolf: cancer stem cells and the epithelial-to-mesenchymal transitionPerspectives of differentiation therapies of acute myeloid leukemia: the search for the molecular basis of patients' variable responses to 1,25-dihydroxyvitamin d and vitamin d analogsHow animal models of leukaemias have already benefited patientsDevelopmental disease and cancer: biological and clinical overlapsA murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.Familiar drugs may prevent cancerPIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemiaChemoprevention of colorectal cancerRetinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cellsIdentification of candidate small-molecule therapeutics to cancer by gene-signature perturbation in connectivity mappingTumor initiating cells in esophageal squamous cell carcinomas express high levels of CD44Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant glioma cellsPathway analysis for drug repositioning based on public database miningTargeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidinesDrug development against metastasis-related genes and their pathways: A rationale for cancer therapyRetinoic acid actions through mammalian nuclear receptors.Open-access synthetic spike-in mRNA-seq data for cancer gene fusions.Characterization of a fusion cDNA (RARA/myl) transcribed from the t(15;17) translocation breakpoint in acute promyelocytic leukemia.Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemiaPhase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies.Differentiation therapy of leukemia: 3 decades of development.Using LongSAGE to Detect Biomarkers of Cervical Cancer Potentially Amenable to Optical Contrast Agent Labelling.All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.
P2860
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P2860
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
description
1988 nî lūn-bûn
@nan
1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@ast
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@en
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@nl
type
label
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@ast
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@en
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@nl
prefLabel
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@ast
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@en
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@nl
P2093
P3181
P1433
P1476
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
@en
P2093
P304
P3181
P407
P577
1988-08-01T00:00:00Z