Identification of candidate small-molecule therapeutics to cancer by gene-signature perturbation in connectivity mapping
about
Combination of a proteomics approach and reengineering of meso scale network models for prediction of mode-of-action for tyrosine kinase inhibitorsConnectivity Mapping for Candidate Therapeutics Identification Using Next Generation Sequencing RNA-Seq DataPrioritizing therapeutics for lung cancer: an integrative meta-analysis of cancer gene signatures and chemogenomic dataTranscriptional data: a new gateway to drug repositioning?BRCA-Monet: a breast cancer specific drug treatment mode-of-action network for treatment effective prediction using large scale microarray database.TAZ expression as a prognostic indicator in colorectal cancer.cudaMap: a GPU accelerated program for gene expression connectivity mapping.Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapiesA gene-signature progression approach to identifying candidate small-molecule cancer therapeutics with connectivity mappingThe prognostic significance of DAPK1 in bladder cancer.In silico methods for drug repurposing and pharmacologySenataxin controls meiotic silencing through ATR activation and chromatin remodeling.Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis.Drug repositioning by applying 'expression profiles' generated by integrating chemical structure similarity and gene semantic similarity.Cystic Fibrosis from Laboratory to Bedside: The Role of A20 in NF-κB-Mediated Inflammation.CD133 in brain tumor: the prognostic factor.Identification and validation of the dopamine agonist bromocriptine as a novel therapy for high-risk myelodysplastic syndromes and secondary acute myeloid leukemia.DAPK1 as an independent prognostic marker in liver cancer.β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer developmentEntinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia.An integrated meta-analysis approach to identifying medications with potential to alter breast cancer risk through connectivity mapping.EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma.CLC-Pred: A freely available web-service for in silico prediction of human cell line cytotoxicity for drug-like compounds.The anti-psychotic drug pimozide is a novel chemotherapeutic for breast cancer
P2860
Q28484913-79B0FAE3-64A1-4FFF-9F8C-A6C9AA4C52AEQ28534334-855A06C8-23CE-4058-BC65-158E3FE478AAQ28544631-357CE505-0AAC-41BD-8251-71B59D56FDC9Q30557854-14B4C484-3F38-45CE-BCD3-377D3244E9B1Q33643334-3D785DC0-CE81-4631-BFAA-51C418B758FFQ34571020-74C57331-8D84-4353-8C21-197E977A5190Q35013482-7070ED2A-0246-4C3E-9D3B-BBB05D2621F5Q35769403-B081F37E-2424-44F8-ADD6-200B454BA26BQ36015110-065DD80E-7E5F-495B-8026-4E0CD4560682Q36339910-C870F110-C3A6-43EA-B707-15E8CFCE98EDQ36837816-10D7A13B-B03A-4E9B-B026-8725ACFABC96Q36882769-FF50DFBB-FC0E-4F73-A1EE-241AA78A63ECQ37065065-323AE75D-0DF8-418B-8F7F-CD99CA995335Q38434869-E17DF569-7DB5-44E2-9259-41F5451E4A01Q38449873-27E020AA-232A-4AD1-8EF9-B849357BCA73Q38722833-ABA683F9-9E42-4324-B852-321CC24C735AQ40140077-02C4F335-3B80-43CF-8096-E3B42CF8D712Q41084560-F7D54A39-08A5-4073-8BB1-31689DD1CF5EQ42683902-5BB4A7B5-27D5-4E88-B9A3-1A38535FA4BBQ45754556-E08AA66B-28BC-4B07-8EAB-2423D874E209Q47098576-C034872F-A514-4023-A1B3-7D421A6B6EABQ47140740-C6C7619F-2B26-432F-A1C1-9D6FCE601E08Q47556436-8451EAF6-331E-4205-BC96-43D7BF62BA63Q58579097-D65454D8-3C17-4F80-8EBF-5DE6A5598EB4
P2860
Identification of candidate small-molecule therapeutics to cancer by gene-signature perturbation in connectivity mapping
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Identification of candidate sm ...... bation in connectivity mapping
@ast
Identification of candidate sm ...... bation in connectivity mapping
@en
Identification of candidate sm ...... bation in connectivity mapping
@nl
type
label
Identification of candidate sm ...... bation in connectivity mapping
@ast
Identification of candidate sm ...... bation in connectivity mapping
@en
Identification of candidate sm ...... bation in connectivity mapping
@nl
prefLabel
Identification of candidate sm ...... bation in connectivity mapping
@ast
Identification of candidate sm ...... bation in connectivity mapping
@en
Identification of candidate sm ...... bation in connectivity mapping
@nl
P2860
P3181
P1433
P1476
Identification of candidate sm ...... bation in connectivity mapping
@en
P2093
Shu-Dong Zhang
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0016382
P407
P577
2011-01-31T00:00:00Z