Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype
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The structural basis of arrestin-mediated regulation of G-protein-coupled receptorsGlucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic SuccessesNovel GLP-1 fusion chimera as potent long acting GLP-1 receptor agonistThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsbeta-Arrestin 1 and 2 stabilize the angiotensin II type I receptor in distinct high-affinity conformations.Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells.Glutamine stimulates biosynthesis and secretion of insulin-like growth factor 2 (IGF2), an autocrine regulator of beta cell mass and function.Gluco-incretins regulate beta-cell glucose competence by epigenetic silencing of Fxyd3 expressionThe GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively.Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin.Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences.The connection between GRKs and various signaling pathways involved in diabetic nephropathy.Physiology and emerging biochemistry of the glucagon-like peptide-1 receptor.Recent advances in understanding GLP-1R (glucagon-like peptide-1 receptor) function.Identifying ligand-specific signalling within biased responses: focus on δ opioid receptor ligands.Molecular Pharmacology of the Incretin Receptors.Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1.Comparative effects of the endogenous agonist glucagon-like peptide-1 (GLP-1)-(7-36) amide and the small-molecule ago-allosteric agent "compound 2" at the GLP-1 receptor.SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor.Rate of Homologous Desensitization and Internalization of the GLP-1 Receptor.β-Arrestin-Biased Agonists of the GLP-1 Receptor from β-Amino Acid Residue Incorporation into GLP-1 Analogues.Investigating Internalization and Intracellular Trafficking of GPCRs: New Techniques and Real-Time Experimental Approaches.Differences between G-Protein-Stabilized Agonist-GPCR Complexes and their Nanobody-Stabilized Equivalents.Beta-arrestin2 as a competitor for GRK2 interaction with the GLP-1 receptor upon receptor activation.Systems analysis of GLP-1 receptor signaling in pancreatic β-cells.Pancreatic alpha cells in diabetic rats express active GLP-1 receptor: Endosomal co-localization of GLP-1/GLP-1R complex functioning through intra-islet paracrine mechanism.Targeting GLP-1 receptor trafficking to improve agonist efficacy.Investigating allosteric effects on the functional dynamics of β2-adrenergic ternary complexes with enhanced-sampling simulations
P2860
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P2860
Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@ast
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@en
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@nl
type
label
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@ast
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@en
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@nl
prefLabel
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@ast
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@en
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@nl
P2093
P3181
P356
P1476
Characterization of glucagon-l ...... gh-affinity receptor phenotype
@en
P2093
Christian E Elling
Lene Martini
Rasmus Jorgensen
P304
P3181
P356
10.1210/ME.2004-0312
P407
P577
2005-03-01T00:00:00Z