Role of ELA region in auto-activation of mutant KIT receptor: a molecular dynamics simulation insight
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Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivityStructure-activity relationships study of mTOR kinase inhibition using QSAR and structure-based drug design approachesIdentification of Dual Natural Inhibitors for Chronic Myeloid Leukemia by Virtual Screening, Molecular Dynamics Simulation and ADMET Analysis.Mutational analysis of FUS gene and its structural and functional role in amyotrophic lateral sclerosis 6.Molecular dynamic simulation reveals damaging impact of RAC1 F28L mutation in the switch I region.Prognostic Value of Her2/neu Expression in Gastrointestinal Stromal Tumors: Immunohistochemical Study.Identification and analysis of driver missense mutations using rotation forest with feature selection.Use of long term molecular dynamics simulation in predicting cancer associated SNPs.The expression and significance of Gal-3 and MUC1 in colorectal cancer and colon cancer.Structure-based design of novel naproxen derivatives targeting monomeric nucleoprotein of Influenza A virus.Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma.Influence of MDM2 polymorphisms on squamous cell carcinoma susceptibility: a meta-analysis.Computational SNP analysis: current approaches and future prospects.Discovery of Potent ALK Inhibitors Using Pharmacophore-Informatics Strategy.In Silico Template Selection of Short Antimicrobial Peptide Viscotoxin for Improving Its Antimicrobial Efficiency in Development of Potential Therapeutic Drugs.Cell-Peptide Specific Interaction Can Inhibit Mycobacterium tuberculosis H37Rv Infection.A meta-analysis of prognostic value of KIT mutation status in gastrointestinal stromal tumorsIdentification of sequence motifs involved in Dengue virus-host interactions.HD5 and HBD1 variants' solvation potential energy correlates with their antibacterial activity against Escherichia coli.Molecular dynamics simulation of the effects of single (S221P) and double (S221P and K216E) mutations in the hemagglutinin protein of influenza A H5N1 virus: a study on host receptor specificity.A Quantitative Measure of Conformational Changes in Apo, Holo and Ligand-Bound Forms of Enzymes.Single Active Site Mutation Causes Serious Resistance of HIV Reverse Transcriptase to Lamivudine: Insight from Multiple Molecular Dynamics Simulations.A quantitative measure of conformational changes in Apo, holo and ligand bound form of enzymes.Computational investigation of molecular mechanism and neuropathological implications in Huntington disease.Biophysical Aspect of Huntingtin Protein During polyQ: An In Silico Insight.Cysteine to Serine Conversion at 111th Position Renders the Disaggregation and Retains the Stabilization of Detrimental SOD1 A4V Mutant Against Amyotrophic Lateral Sclerosis in Human-A Discrete Molecular Dynamics Study.Deciphering the Molecular Effects of Mutations on ATRX Cause ATRX Syndrome: A Molecular Dynamics Study.Computational investigation of the human SOD1 mutant, Cys146Arg, that directs familial amyotrophic lateral sclerosis.Casting the critical regions in nucleotide binding oligomerization domain 2 protein: a signature mediated structural dynamics approach.Dynamics of the active site loops in catalyzing aminoacylation reaction in seryl and histidyl tRNA synthetases.Impact of point mutation P29S in RAC1 on tumorigenesis.In silico approach to explore the disruption in the molecular mechanism of human hyaluronidase 1 by mutant E268K that directs Natowicz syndrome.In-silico screening of cancer associated mutation on PLK1 protein and its structural consequences.Biophysical aspect of phosphatidylinositol 3-kinase and role of oncogenic mutants (E542K & E545K).Investigation of Paclitaxel Resistant R306C Mutation in β-Tubulin—A Computational Approach.AKT kinase pathway: a leading target in cancer research.Mutational Analysis on Membrane Associated Transporter Protein (MATP) and Their Structural Consequences in Oculocutaeous Albinism Type 4 (OCA4)-A Molecular Dynamics Approach.Structural analysis of oncogenic mutation of isocitrate dehydrogenase 1.Unraveling the molecular effects of mutation L270P on Wiskkot-Aldrich syndrome protein: insights from molecular dynamics approach.
P2860
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P2860
Role of ELA region in auto-activation of mutant KIT receptor: a molecular dynamics simulation insight
description
2014 nî lūn-bûn
@nan
2014 թուականին հրատարակուած գիտական յօդուած
@hyw
2014 թվականին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Role of ELA region in auto-act ...... ar dynamics simulation insight
@ast
Role of ELA region in auto-act ...... ar dynamics simulation insight
@en
Role of ELA region in auto-act ...... ar dynamics simulation insight
@nl
type
label
Role of ELA region in auto-act ...... ar dynamics simulation insight
@ast
Role of ELA region in auto-act ...... ar dynamics simulation insight
@en
Role of ELA region in auto-act ...... ar dynamics simulation insight
@nl
prefLabel
Role of ELA region in auto-act ...... ar dynamics simulation insight
@ast
Role of ELA region in auto-act ...... ar dynamics simulation insight
@en
Role of ELA region in auto-act ...... ar dynamics simulation insight
@nl
P2860
P3181
P1476
Role of ELA region in auto-act ...... ar dynamics simulation insight
@en
P2093
Rituraj Purohit
P2860
P304
P3181
P356
10.1080/07391102.2013.803264
P407
P577
2014-01-01T00:00:00Z