Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry.

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry.

Item
http://www.wikidata.org/entity/Q33839013
Unique domain appended to vertebrate tRNA synthetase is essential for vascular developmentRole of ELA region in auto-activation of mutant KIT receptor: a molecular dynamics simulation insightHotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivityActivation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases.Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactionsEpitope mapping of a 95 kDa antigen in complex with antibody by solution-phase amide backbone hydrogen/deuterium exchange monitored by Fourier transform ion cyclotron resonance mass spectrometry.Nucleotide-induced conformational changes of tetradecameric GroEL mapped by H/D exchange monitored by FT-ICR mass spectrometryPlatelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1Hydrogen exchange mass spectrometry of functional membrane-bound chemotaxis receptor complexesMolecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit.HDX-MS takes centre stage at unravelling kinase dynamics.Protein conformation ensembles monitored by HDX reveal a structural rationale for abscisic acid signaling protein affinities and activities.
P2860

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry.

Item
http://www.wikidata.org/entity/Q33839013
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Drug binding and resistance me ...... hange FTICR mass spectrometry.
@ast
Drug binding and resistance me ...... hange FTICR mass spectrometry.
@en
type
label
Drug binding and resistance me ...... hange FTICR mass spectrometry.
@ast
Drug binding and resistance me ...... hange FTICR mass spectrometry.
@en
prefLabel
Drug binding and resistance me ...... hange FTICR mass spectrometry.
@ast
Drug binding and resistance me ...... hange FTICR mass spectrometry.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Drug binding and resistance me ...... change FTICR mass spectrometry
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932