Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart - Wikidata - awgldk - TriplyDB

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart

http://www.wikidata.org/entity/Q28293128

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Plakoglobin: role in tumorigenesis and metastasis A new perspective on intercalated disc organization: implications for heart disease Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells Many roads lead to a broken heart: the genetics of dilated cardiomyopathy.Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy Assessment of splice variant-specific functions of desmocollin 1 in the skin The desmosome Defining desmosomal plakophilin-3 interactions The amino-terminal domain of desmoplakin binds to plakoglobin and clusters desmosomal cadherin-plakoglobin complexes Direct Ca2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion Defining the interactions between intermediate filaments and desmosomes Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin Xin proteins and intercalated disc maturation, signaling and diseases Mutations with pathogenic potential in proteins located in or at the composite junctions of the intercalated disk connecting mammalian cardiomyocytes: a reference thesaurus for arrhythmogenic cardiomyopathies and for Naxos and Carvajal diseases Differential interaction of plakoglobin and beta-catenin with the ubiquitin-proteasome system Axin directly interacts with plakoglobin and regulates its stability Alterations at the intercalated disk associated with the absence of muscle LIM protein The Armadillo family protein p0071 is a VE-cadherin- and desmoplakin-binding protein Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling A possible role of catenin dyslocalization in pemphigus vulgaris pathogenesis Genetic bases of arrhythmogenic right ventricular Cardiomyopathy Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture Normalization of Naxos plakoglobin levels restores cardiac function in mice Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis Mechanisms of disease: molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling Lack of plakoglobin leads to lethal congenital epidermolysis bullosa: a novel clinico-genetic entity Requirement for beta-catenin in anterior-posterior axis formation in mice The function of plakophilin 1 in desmosome assembly and actin filament organization Intermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength Circulating tumor cell clusters-associated gene plakoglobin and breast cancer survival.Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling.Ultrastructural analysis of development of myocardium in calreticulin-deficient mice Complete loss of murine Xin results in a mild cardiac phenotype with altered distribution of intercalated discs.

P2860

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P2860

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart

http://www.wikidata.org/entity/Q28293128

description

1996 nî lūn-bûn

@nan

1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1996年の論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年论文

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name

Targeted mutation of plakoglob ...... mosomes in the embryonic heart

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Targeted mutation of plakoglob ...... mosomes in the embryonic heart

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Targeted mutation of plakoglob ...... mosomes in the embryonic heart

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type

label

Targeted mutation of plakoglob ...... mosomes in the embryonic heart

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Targeted mutation of plakoglob ...... mosomes in the embryonic heart

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Targeted mutation of plakoglob ...... mosomes in the embryonic heart

@nl

prefLabel

Targeted mutation of plakoglob ...... mosomes in the embryonic heart

@ast

Targeted mutation of plakoglob ...... mosomes in the embryonic heart

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Targeted mutation of plakoglob ...... mosomes in the embryonic heart

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Targeted mutation of plakoglob ...... mosomes in the embryonic heart

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P2093

B Ledermann

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C Birchmeier

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C Grund

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C Thalhammer

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F Vogel

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M Behrend

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P Ruiz

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U Günthert

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V Brinkmann

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W Birchmeier

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P2860

Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin

Band 6 protein, a major constituent of desmosomes from stratified epithelia, is a novel member of the armadillo multigene family

Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins

Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere

The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

Association of the APC gene product with beta-catenin

Identification of plakoglobin domains required for association with N-cadherin and alpha-catenin

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

P304

215-25

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scholarly article

P356

10.1083/JCB.135.1.215

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P433

1

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135

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1996-10-01T00:00:00Z

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8858175

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2121015

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