Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling - Wikidata - awgldk - TriplyDB

Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling

Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling

http://www.wikidata.org/entity/Q28303564

about

Xin proteins and intercalated disc maturation, signaling and diseases Desmosome regulation and signaling in disease Mutations with pathogenic potential in proteins located in or at the composite junctions of the intercalated disk connecting mammalian cardiomyocytes: a reference thesaurus for arrhythmogenic cardiomyopathies and for Naxos and Carvajal diseases N-cadherin/catenin complex as a master regulator of intercalated disc function Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy Normalization of Naxos plakoglobin levels restores cardiac function in mice Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis Mechanistic basis of desmosome-targeted diseases Integrating animal models and in vitro tissue models to elucidate the role of desmosomal proteins in diseases.Cardiac telocytes - their junctions and functional implications.Arrhythmogenic right ventricular cardiomyopathy mutations alter shear response without changes in cell-cell adhesion.Mechanotransduction in cardiac hypertrophy and failure.Nuclear signaling from cadherin adhesion complexes Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.Phospholamban R14del mutation in patients diagnosed with dilated cardiomyopathy or arrhythmogenic right ventricular cardiomyopathy: evidence supporting the concept of arrhythmogenic cardiomyopathy.Beyond cell adhesion: the role of armadillo proteins in the heart Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.γ-Catenin at adherens junctions: mechanism and biologic implications in hepatocellular cancer after β-catenin knockdown.New insights into the roles of Xin repeat-containing proteins in cardiac development, function, and disease.Plakoglobin as a regulator of desmocollin gene expression.Desmosomes: new perpetrators in tumour suppression Experimental gastritis leads to anxiety- and depression-like behaviors in female but not male rats.Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model.Trim32 reduces PI3K-Akt-FoxO signaling in muscle atrophy by promoting plakoglobin-PI3K dissociation.Cell-cell connectivity: desmosomes and disease.Pathophysiology of arrhythmogenic cardiomyopathy.Desmosomes in the heart: a review of clinical and mechanistic analyses.Alterations in cell adhesion proteins and cardiomyopathy.Arrhythmogenic cardiomyopathy: a disease of intercalated discs.Cell adhesion in epidermal development and barrier formation.Myozap Deficiency Promotes Adverse Cardiac Remodeling via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and β-Catenin/GSK-3β Protein Signaling.Cell models of arrhythmogenic cardiomyopathy: advances and opportunities.Pathophysiology and prevention of sudden cardiac death.Telocytes of Fascial Structures.Cardiac mesenchymal stromal cells are a source of adipocytes in arrhythmogenic cardiomyopathy.Animal models of arrhythmogenic right ventricular cardiomyopathy: what have we learned and where do we go? Insight for therapeutics.Unmasking the molecular link between arrhythmogenic cardiomyopathy and Brugada syndrome.HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity.Wnt/β-catenin pathway in arrhythmogenic cardiomyopathy.Hippo activation in arrhythmogenic cardiomyopathy.

P2860

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P2860

Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling

http://www.wikidata.org/entity/Q28303564

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

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Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

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Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

@nl

type

label

Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

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Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

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Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

@nl

prefLabel

Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

@ast

Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

@en

Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

@nl

P1433

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P1433

Molecular and Cellular Biology

P1476

Cardiac tissue-restricted dele ...... on of {beta}-catenin signaling

@en

P2093

David Swope

http://www.w3.org/2001/XMLSchema#string

Eliane J Muller

http://www.w3.org/2001/XMLSchema#string

Glenn L Radice

http://www.w3.org/2001/XMLSchema#string

Jifen Li

http://www.w3.org/2001/XMLSchema#string

Lan Cheng

http://www.w3.org/2001/XMLSchema#string

Natalia Raess

http://www.w3.org/2001/XMLSchema#string

P2860

Arrhythmogenic right ventricular cardiomyopathy/dysplasia

Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin

A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy

Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy

Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line

Protein kinase cascades in the regulation of cardiac hypertrophy

Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy

Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth

P304

1134-44

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scholarly article

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10.1128/MCB.01025-10

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P407

P433

6

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P478

31

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2011-03-01T00:00:00Z

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21245375

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P932

3067899

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