Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling
about
Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signalingSTAT4 requires the N-terminal domain for efficient phosphorylationRecruitment of Stat4 to the human interferon-alpha/beta receptor requires activated Stat2Systems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms.Interleukin-12 preserves the cutaneous physical and immunological barrier after radiation exposure.Polymorphism of the 5' flanking region of the IL-12 receptor beta2 gene partially determines the clinical types of leprosy through impaired transcriptional activityStepwise regulation of TH1 responses in autoimmunity: IL-12-related cytokines and their receptors.Biology and significance of the JAK/STAT signalling pathways.IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1.Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases.Role of the Stat4 N domain in receptor proximal tyrosine phosphorylation.Pre-assembly of STAT4 with the human IFN-alpha/beta receptor-2 subunit is mediated by the STAT4 N-domain.Functional analysis of differences in transcriptional activity conferred by genetic variants in the 5' flanking region of the IL12RB2 gene.Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor.Human microglial cells express a functional IL-12 receptor and produce IL-12 following IL-12 stimulation.STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interactionp-Y693-STAT4 dimerizesY693-STAT4 dimer translocates to the nucleusSelective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2.STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus.
P2860
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P2860
Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Identification of a STAT4 bind ...... eceptor required for signaling
@ast
Identification of a STAT4 bind ...... eceptor required for signaling
@en
Identification of a STAT4 bind ...... eceptor required for signaling
@nl
type
label
Identification of a STAT4 bind ...... eceptor required for signaling
@ast
Identification of a STAT4 bind ...... eceptor required for signaling
@en
Identification of a STAT4 bind ...... eceptor required for signaling
@nl
prefLabel
Identification of a STAT4 bind ...... eceptor required for signaling
@ast
Identification of a STAT4 bind ...... eceptor required for signaling
@en
Identification of a STAT4 bind ...... eceptor required for signaling
@nl
P2093
P2860
P3181
P356
P1476
Identification of a STAT4 bind ...... eceptor required for signaling
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.274.4.1875
P407
P577
1999-01-22T00:00:00Z