Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain
about
POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory gangliaBrn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiationSortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling.Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neuronsA central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programsVGLUTs and Glutamate Synthesis-Focus on DRG Neurons and PainA transcription factor code defines nine sensory interneuron subtypes in the mechanosensory area of the spinal cordDifferent requirements for GFRα2-signaling in three populations of cutaneous sensory neuronsUncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptorLoss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone developmentMolecular control of the neural crest and peripheral nervous system developmentThe role of GDNF family ligand signalling in the differentiation of sympathetic and dorsal root ganglion neuronsTlx3 and Runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptorsBrn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglionMouse DRG Cell Line with Properties of NociceptorsIncoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptorsProtein tyrosine phosphatase receptor type O regulates development and function of the sensory nervous system.LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural developmentSignals and switches in Mammalian neural crest cell differentiationThe evolutionary origin of the Runx/CBFbeta transcription factors--studies of the most basal metazoansTNF-α/TNFR1 signaling is required for the development and function of primary nociceptors.In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization.RUNX1 and its understudied role in breast cancerAn ensemble of regulatory elements controls Runx3 spatiotemporal expression in subsets of dorsal root ganglia proprioceptive neuronsDevelopmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesisFactors that regulate embryonic gustatory development.A SAGE-based screen for genes expressed in sub-populations of neurons in the mouse dorsal root ganglion.Molecular characterization of the mouse superior lateral parabrachial nucleus through expression of the transcription factor Runx1.In vitro and in vivo effects on neural crest stem cell differentiation by conditional activation of Runx1 short isoform and its effect on neuropathic pain behavior.Development of multilineage adult hematopoiesis in the zebrafish with a runx1 truncation mutationRunx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin.Tlx3 Function in the Dorsal Root Ganglion is Pivotal to Itch and Pain Sensations.Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniatesDeletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathwayPatterned assembly and neurogenesis in the chick dorsal root ganglion.Spinal mediators that may contribute selectively to antinociceptive tolerance but not other effects of morphine as revealed by deletion of GluR5The development of peripheral cold neural circuits based on TRPM8 expression.Phenotypic switching of nonpeptidergic cutaneous sensory neurons following peripheral nerve injuryRegulation of the Na,K-ATPase gamma-subunit FXYD2 by Runx1 and Ret signaling in normal and injured non-peptidergic nociceptive sensory neurons.Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function
P2860
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P2860
Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@ast
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@en
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@nl
type
label
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@ast
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@en
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@nl
prefLabel
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@ast
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@en
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@nl
P2093
P1433
P1476
Runx1 determines nociceptive s ...... r thermal and neuropathic pain
@en
P2093
Chih-Li Chen
Clifford J Woolf
Daniel C Broom
Joriene C de Nooij
Omar Abdel Samad
Thomas M Jessell
P304
P356
10.1016/J.NEURON.2005.10.036
P407
P577
2006-02-02T00:00:00Z