Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway - Wikidata - awgldk - TriplyDB

Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway

Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway

http://www.wikidata.org/entity/Q33927079

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NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes PI(5)P regulates autophagosome biogenesis Clarifying lysosomal storage diseases Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons Phosphatidylinositol 3,5-bisphosphate: low abundance, high significance Early etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?Sorting through the roles of beclin 1 in microglia and neurodegeneration Identifying local and descending inputs for primary sensory neurons.Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy A Review of Genome-Wide Association Studies of Stimulant and Opioid Use Disorders Teaching the basics of autophagy and mitophagy to redox biologists--mechanisms and experimental approaches Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella A PIK3C3-ankyrin-B-dynactin pathway promotes axonal growth and multiorganelle transport.The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.Significant determinants of mouse pain behaviour.The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy.Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier Vps15 is required for stress induced and developmentally triggered autophagy and salivary gland protein secretion in Drosophila.Risk of false positive genetic associations in complex traits with underlying population structure: a case study Atg7 enhances host defense against infection via downregulation of superoxide but upregulation of nitric oxide Reactivation of Lysosomal Ca2+ Efflux Rescues Abnormal Lysosomal Storage in FIG4-Deficient Cells Novel method to assess axonal excitability using channelrhodopsin-based photoactivation Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis Temporal control of gene deletion in sensory ganglia using a tamoxifen-inducible Advillin-Cre-ERT2 recombinase mouse.Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function.Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3 Lyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related Phagocytosis The phospholipase D1 pathway modulates macroautophagy Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis.Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.Activating Injury-Responsive Genes with Hypoxia Enhances Axon Regeneration through Neuronal HIF-1α.G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.Acute manipulation of phosphoinositide levels in cells.

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Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway

http://www.wikidata.org/entity/Q33927079

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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name

Deletion of PIK3C3/Vps34 in se ...... but not the autophagic pathway

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Deletion of PIK3C3/Vps34 in se ...... but not the autophagic pathway

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type

label

Deletion of PIK3C3/Vps34 in se ...... but not the autophagic pathway

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Deletion of PIK3C3/Vps34 in se ...... but not the autophagic pathway

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prefLabel

Deletion of PIK3C3/Vps34 in se ...... but not the autophagic pathway

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Deletion of PIK3C3/Vps34 in se ...... but not the autophagic pathway

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Proceedings of the National Academy of Sciences of the United States of America

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Deletion of PIK3C3/Vps34 in se ...... but not the autophagic pathway

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Bao-Xia Han

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Fan Wang

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Hiroshi Hasegawa

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Liangli Wang

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Priyanka Amin

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Shinjiro Kaneko

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Xiang Zhou

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Youwen He

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P2860

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system

The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase

Mutations in PIP5K3 are associated with François-Neetens mouchetée fleck corneal dystrophy

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

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20439739

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