The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter
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Roles of BRCA1 in centrosome duplicationHighlight: BRCA1 and BRCA2 proteins in breast cancerCrystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stressComparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysisAre Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related?Examination of the expanding pathways for the regulation of p21 expression and activity.BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear exportAdenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domainsc-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cellsDisruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein bindingBRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transitionBRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damageNFBD1/MDC1 associates with p53 and regulates its function at the crossroad between cell survival and death in response to DNA damageBRCA1 and Oxidative StressEts-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements inMapping and conformational characterization of the DNA-binding region of the breast cancer susceptibility protein BRCA1.BRCA1 interaction with human papillomavirus oncoproteins.The p53 core domain is a molten globule at low pH: functional implications of a partially unfolded structure.DNA polymerase mu, a candidate hypermutase?Ovarian cancer: pathology, biology, and disease modelsRole of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation.Emerging roles of BRCA1 alternative splicing.Tumor suppressor p53 is required to modulate BRCA1 expression.Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear fociRegulation of the BRCA1 gene by an SRC3/53BP1 complexDNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation.Strategies for manipulating the p53 pathway in the treatment of human cancer.Lessons learned from BRCA1 and BRCA2.The pathology of familial breast cancer: How do the functions of BRCA1 and BRCA2 relate to breast tumour pathology?BRCA1 and prostate cancer.Functional dissection of transcription factor ZBRK1 reveals zinc fingers with dual roles in DNA-binding and BRCA1-dependent transcriptional repression.Effects on human transcriptome of mutated BRCA1 BRCT domain: a microarray study.SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activityRegulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation.The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.The function of BRCA1 in DNA damage response.Ubiquitin and breast cancer.SUMO1 negatively regulates BRCA1-mediated transcription, via modulation of promoter occupancy
P2860
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P2860
The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@ast
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@en
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@nl
type
label
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@ast
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@en
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@nl
prefLabel
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@ast
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@en
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@nl
P2093
P2860
P356
P1433
P1476
The second BRCT domain of BRCA ...... from the p21WAF1/CIP1 promoter
@en
P2093
P2860
P2888
P356
10.1038/SJ.ONC.1202323
P407
P577
1999-01-07T00:00:00Z
P5875
P6179
1037438019