Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks
about
The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expressionDisease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions.The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transitionMutation in human desmoplakin domain binding to plakoglobin causes a dominant form of arrhythmogenic right ventricular cardiomyopathyEnvoplakin, a novel precursor of the cornified envelope that has homology to desmoplakinPhosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431Making a connection: direct binding between keratin intermediate filaments and desmosomal proteinsBinding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament bindingBasic amino acid residue cluster within nuclear targeting sequence motif is essential for cytoplasmic plectin-vimentin network junctionsBreaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assemblyDynamics of human keratin 18 phosphorylation: polarized distribution of phosphorylated keratins in simple epithelial tissuesThe amino-terminal domain of desmoplakin binds to plakoglobin and clusters desmosomal cadherin-plakoglobin complexesDefining the interactions between intermediate filaments and desmosomesPeriplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakinSubcellular distribution of envoplakin and periplakin: insights into their role as precursors of the epidermal cornified envelopeUnique role for the periplakin tail in intermediate filament association: specific binding to keratin 8 and vimentinThe Armadillo family protein p0071 is a VE-cadherin- and desmoplakin-binding proteinCo-assembly of envoplakin and periplakin into oligomers and Ca(2+)-dependent vesicle binding: implications for cornified cell envelope formation in stratified squamous epitheliaPlakins: goliaths that link cell junctions and the cytoskeletonLoss of desmoplakin tail causes lethal acantholytic epidermolysis bullosaPlakophilin 2 couples actomyosin remodeling to desmosomal plaque assembly via RhoA.The 70-kDa heat shock proteins associate with glandular intermediate filaments in an ATP-dependent mannerRequirement of plakophilin 2 for heart morphogenesis and cardiac junction formationDesmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkageTargeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heartMechanistic basis of desmosome-targeted diseasesLoss of desmoplakin isoform I causes early onset cardiomyopathy and heart failure in a Naxos-like syndromeElimination of epiplakin by gene targeting results in acceleration of keratinocyte migration in mice.The function of plakophilin 1 in desmosome assembly and actin filament organizationIntermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strengthEpiplakin, a novel member of the Plakin family originally identified as a 450-kDa human epidermal autoantigen. Structure and tissue localization.Directed expression of a chimeric type II keratin partially rescues keratin 5-null mice.Structure and regulation of the envoplakin gene.Compound heterozygous desmoplakin mutations result in a phenotype with a combination of myocardial, skin, hair, and enamel abnormalitiesInsights from a desmoplakin mutation identified in lethal acantholytic epidermolysis bullosaInteraction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.Spectraplakins: master orchestrators of cytoskeletal dynamics.Molecular abnormalities of the desmosomal protein desmoplakin in human disease.Desmoplakin assembly dynamics in four dimensions: multiple phases differentially regulated by intermediate filaments and actin.Protein zero, a nervous system adhesion molecule, triggers epithelial reversion in host carcinoma cells.
P2860
Q24291264-4722A4E2-6576-4C34-AB36-FDA1392F700FQ24304113-66810354-D848-4D78-9132-D3167B12550FQ24309569-53704572-AA71-45B3-A39D-21881519EF64Q24310389-3B88E859-3E1A-4D5E-9724-7F11C53C19CBQ24313053-5FD50147-D5AD-4445-8A41-224BA5D0AF4CQ24324509-4A949A8C-A11F-4265-96CB-8E964EB04AF3Q24651318-D4F05280-F6EB-46BC-A05B-60E11D9BF39EQ24670751-9B73B941-AC7F-4DEE-AA5A-B4E83DC3F022Q24671487-BD97F63C-B4F3-4FA8-92FA-B1617E688105Q24671724-AE348627-15AC-40B4-8A82-36F22E375047Q24672308-0913E4CD-8F2E-4002-911C-675FB638E873Q24676676-D7F9EB1A-8F6B-402C-8A3D-FB342175A33AQ24680223-30AE8F6A-EE73-4F06-9CC4-0A1639C5B131Q24683575-AA4F0CBE-50A5-4406-8E5E-BECE97933620Q24683828-65C857F5-EEE7-407B-B9D1-689980599D40Q28205520-530E5446-E9F4-4ADD-9BAE-282E001E4A78Q28214513-0A389583-7DE2-43C4-854C-A2580F3CD273Q28251726-6633CA78-A402-4B3F-A211-93DCB7D4C911Q28270016-510ED712-7DDF-420D-A6FD-E31F86C60DD4Q28273322-3360906E-5104-4D90-AD3F-FDF49CE5F40AQ28285534-CCAD1353-1A2D-4A0B-9817-B0E647F87EC0Q28287322-174A24FF-1F87-45AC-B333-7B69270B362FQ28287493-43464569-B76A-42ED-916D-02F6A03353EFQ28292286-87217F5D-3D1B-4B5D-B57F-B5684EFE99DEQ28293128-AF9A2D3F-14C1-4B18-9465-980BB516E1D1Q28295898-3EEAA3BC-7E3E-413D-ABFB-D32C22D77875Q28296280-39FE05CA-C392-46FB-A121-BC37B69D5659Q28585722-B5D036E5-65D7-4B3F-A87F-CB339E9104B1Q30321137-E9F1E24C-B570-4E92-BCF3-0050B27C5EA1Q30441902-D37193AA-9831-4BB6-8691-14CDC2BCC096Q30661678-E324D716-E4F1-441D-8D04-22CB3CA82978Q33888515-77AD8B2B-AFFC-4E44-878D-E57AE9292305Q33896689-8A7491EC-B1A3-4600-89BF-1152BF879FC0Q34581986-102EE3C4-A823-4D73-BC41-9A3225D4E10BQ34700774-1D82BF3D-9458-4F01-BD5A-633E7D663102Q35153581-8764FB1A-B7FC-4C89-9852-5C3E5D802D9EQ35962308-77C73298-ED2F-4846-9D65-C1FC75A44D29Q36088262-91C4C7E3-BBC7-412B-9A35-9571771C4A6BQ36320545-24300C12-27CF-4A5B-A3FD-9D0E5E72FC72Q36382782-5BC3D5E1-1EE8-4DF8-ABB5-8AC0FE571C8C
P2860
Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks
description
1993 nî lūn-bûn
@nan
1993 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Functional analysis of desmopl ...... intermediate filament networks
@ast
Functional analysis of desmopl ...... intermediate filament networks
@en
Functional analysis of desmopl ...... intermediate filament networks
@nl
type
label
Functional analysis of desmopl ...... intermediate filament networks
@ast
Functional analysis of desmopl ...... intermediate filament networks
@en
Functional analysis of desmopl ...... intermediate filament networks
@nl
prefLabel
Functional analysis of desmopl ...... intermediate filament networks
@ast
Functional analysis of desmopl ...... intermediate filament networks
@en
Functional analysis of desmopl ...... intermediate filament networks
@nl
P2093
P2860
P356
P1476
Functional analysis of desmopl ...... intermediate filament networks
@en
P2093
C M Corcoran
E A Bornslaeger
M L Virata
T S Stappenbeck
P2860
P304
P356
10.1083/JCB.123.3.691
P407
P577
1993-11-01T00:00:00Z