Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue - Wikidata - awgldk - TriplyDB

Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue

Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue

http://www.wikidata.org/entity/Q28300082

about

Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure MicroRNA-regulated viral vectors for gene therapy Gene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translation Model-specific selection of molecular targets for heart failure gene therapy Gene delivery technologies for cardiac applications Cardiovascular gene therapy for myocardial infarction Gene therapy targets in heart failure: the path to translation Calcium mishandling in diastolic dysfunction: mechanisms and potential therapies Characterization of regional left ventricular function in nonhuman primates using magnetic resonance imaging biomarkers: a test-retest repeatability and inter-subject variability study Cardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failure S100A1 in human heart failure: lack of recovery following left ventricular assist device support Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model S100A1 genetically targeted therapy reverses dysfunction of human failing cardiomyocytes.S100A1 in cardiovascular health and disease: closing the gap between basic science and clinical therapy Targeting S100A1 in heart failure S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling S100A1: Structure, Function, and Therapeutic Potential Aiming for the heart: targeted delivery of drugs to diseased cardiac tissue S100A1: A novel and essential molecular component for postischemic angiogenesis S100A1: a multifaceted therapeutic target in cardiovascular disease AAV-mediated gene therapy for heart failure: enhancing contractility and calcium handling Small and large animal models in cardiac contraction research: advantages and disadvantages Regulation of in vivo cardiac contractility by phospholemman: role of Na+/Ca2+ exchange.Gene transfer in skeletal and cardiac muscle using recombinant adeno-associated virus Differential effects of S100 proteins A2 and A6 on cardiac Ca(2+) cycling and contractile performance.Heart failure management: the present and the future.S100A1: a regulator of striated muscle sarcoplasmic reticulum Ca2+ handling, sarcomeric, and mitochondrial function The potential of adeno-associated viral vectors for gene delivery to muscle tissue.Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat.Rescuing the failing heart by targeted gene transfer Caveolin-1 deficiency exacerbates cardiac dysfunction and reduces survival in mice with myocardial infarction Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1.Activation of cardiac adenylyl cyclase expression increases function of the failing ischemic heart in mice.AAV vectors for cardiac gene transfer: experimental tools and clinical opportunities.S100A1 (S100 calcium binding protein A1)Blockade of β-adrenoceptors restores the GRK2-mediated adrenal α(2) -adrenoceptor-catecholamine production axis in heart failure Potential of gene therapy as a treatment for heart failure New signaling pathways associated with increased cardiac adenylyl cyclase 6 expression: implications for possible congestive heart failure therapy.Liquid jet delivery method featuring S100A1 gene therapy in the rodent model following acute myocardial infarction.

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Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue

http://www.wikidata.org/entity/Q28300082

description

2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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Stable myocardial-specific AAV ...... unctional heart failure rescue

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Stable myocardial-specific AAV ...... unctional heart failure rescue

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Abhijit Dasgupta

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Andrea D Eckhart

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Andrew Remppis

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J Kurt Chuprun

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Stephen Soltys

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Sven T Pleger

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