Estimating the cost of new drug development: is it really 802 million dollars?
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Stable isotope-resolved metabolomics and applications for drug development'RE:fine drugs': an interactive dashboard to access drug repurposing opportunitiesDrug Repurposing Is a New Opportunity for Developing Drugs against Neuropsychiatric DisordersMicroengineering in cardiovascular research: new developments and translational applications.Preclinical mouse cancer models: a maze of opportunities and challenges.Novel methods and technologies for 21st-century clinical trials: a review.Leveraging 3D chemical similarity, target and phenotypic data in the identification of drug-protein and drug-adverse effect associationsTherapeutic Manipulation of Ageing: Repurposing Old Dogs and Discovering New TricksMedication Nonadherence, "Professional Subjects," and Apparent Placebo Responders: Overlapping Challenges for Medications DevelopmentHow drugs are developed and approved by the FDA: current process and future directionsKey cost drivers of pharmaceutical clinical trials in the United StatesUsing gene expression signatures to identify novel treatment strategies in gulf war illnessPriorities for the Priority Review VoucherA multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homologyAdvancing drug innovation for neglected diseases-criteria for lead progressionFinancing of U.S. biomedical research and new drug approvals across therapeutic areasThe Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathwayAn open source business model for malariaA meta-analysis of threats to valid clinical inference in preclinical research of sunitinibInferring drug-disease associations based on known protein complexesImproved genome-scale multi-target virtual screening via a novel collaborative filtering approach to cold-start problem.A crowdsourcing evaluation of the NIH chemical probesBiodefense countermeasures: the impact of Title IV of the US Pandemic and All-Hazards Preparedness ActCryptosporidium and Giardia in Africa: current and future challenges.Cryptosporidium in humans and animals-a one health approach to prophylaxis.Photoacoustic signal characterization of cancer treatment response: Correlation with changes in tumor oxygenation.Mechanistic systems modeling to guide drug discovery and developmentAccelerating drug discovery via organs-on-chips.Ingestion-controlling network: what's language got to do with it?Identification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria boxInferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation.Creating a Common Data Model for Comparative Effectiveness with the Observational Medical Outcomes PartnershipUsing Social Media Data to Identify Potential Candidates for Drug Repurposing: A Feasibility Study.Prediction of new drug indications based on clinical data and network modularity.Prediction of animal clearance using naïve Bayesian classification and extended connectivity fingerprints.Cost effectiveness of pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 before irinotecan administration for metastatic colorectal cancer.Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.Cyanobacteria: an emerging source for drug discovery.Oral cancer therapy: policy implications for the uninsured and underinsured populations.Characterizing the diversity and biological relevance of the MLPCN assay manifold and screening set.
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P2860
Estimating the cost of new drug development: is it really 802 million dollars?
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2006 nî lūn-bûn
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2006 թուականին հրատարակուած գիտական յօդուած
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2006 թվականին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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Estimating the cost of new drug development: is it really 802 million dollars?
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Estimating the cost of new drug development: is it really 802 million dollars?
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Estimating the cost of new drug development: is it really 802 million dollars?
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Estimating the cost of new drug development: is it really 802 million dollars?
@ast
Estimating the cost of new drug development: is it really 802 million dollars?
@en
Estimating the cost of new drug development: is it really 802 million dollars?
@nl
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Estimating the cost of new drug development: is it really 802 million dollars?
@ast
Estimating the cost of new drug development: is it really 802 million dollars?
@en
Estimating the cost of new drug development: is it really 802 million dollars?
@nl
P3181
P356
P1433
P1476
Estimating the cost of new drug development: is it really 802 million dollars?
@en
P2093
Christopher P Adams
Van V Brantner
P3181
P356
10.1377/HLTHAFF.25.2.420
P407
P577
2006-01-01T00:00:00Z