The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles - Wikidata - awgldk - TriplyDB

The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles

The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles

http://www.wikidata.org/entity/Q28303245

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Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB Crystal structure of human cyclin K, a positive regulator of cyclin-dependent kinase 9 Novel Molecular Markers for Breast Cancer Cyclin Box Structure of the P-TEFb Subunit Cyclin T1 Derived from a Fusion Complex with EIAV Tat Structural Diversity of the Active N-Terminal Kinase Domain of p90 Ribosomal S6 Kinase 2 Molecular basis of differential selectivity of cyclobutyl-substituted imidazole inhibitors against CDKs: insights for rational drug design Drug targets for cell cycle dysregulators in leukemogenesis: in silico docking studies Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.Cyclin E-dependent protein kinase activity regulates niche retention of Drosophila ovarian follicle stem cells.Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding.Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21 Centrosomal localization of cyclins E and A: structural similarities and functional differences Polyphony: superposition independent methods for ensemble-based drug discovery.Insights on Structural Characteristics and Ligand Binding Mechanisms of CDK2 Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming.A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.Drosophila follicle cell amplicons as models for metazoan DNA replication: a cyclinE mutant exhibits increased replication fork elongation A transcriptome-based model of central memory CD4 T cell death in HIV infection.ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6.A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation.Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages.Comparative Analysis of the Effects of Two Probiotic Bacterial Strains on Metabolism and Innate Immunity in the RAW 264.7 Murine Macrophage Cell Line.Novel 4-(4-substituted-thiazol-2-ylamino)-N-(pyridin-2-yl)-benzenesulfonamides as cytotoxic and radiosensitizing agents.Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.A cancer-derived mutation in the PSTAIRE helix of cyclin-dependent kinase 2 alters the stability of cyclin binding.Post-translational modification and stability of low molecular weight cyclin E.Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycle Covalent Modification of CDK2 by 4-Hydroxynonenal as a Mechanism of Inhibition of Cell Cycle Progression.Distinct properties of cyclin-dependent kinase complexes containing cyclin A1 and cyclin A2.NDGA-P21, a novel derivative of nordihydroguaiaretic acid, inhibits glioma cell proliferation and stemness.PolyC-binding proteins enhance expression of the CDK2 cell cycle regulatory protein via alternative splicing.Substrate recognition and ubiquitination of SCFSkp2/Cks1 ubiquitin-protein isopeptide ligase.Different mechanisms of CDK5 and CDK2 activation as revealed by CDK5/p25 and CDK2/cyclin A dynamics.Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: dynamic and energetic polarization of the kinase lobes may determine divergence of the regulatory mechanisms.The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition.Structural insights into the functional diversity of the CDK-cyclin family

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The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles

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2005 nî lūn-bûn

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2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2005 թվականի փետրվարին հրատարակված գիտական հոդված

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2005年の論文

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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The EMBO Journal

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The structure of cyclin E1/CDK ...... ion and CDK2-independent roles

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Edward D Lowe

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Elena Dubinina

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Louise N Johnson

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Nick R Brown

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Reiko Honda

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Vicky Skamnaki

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P2860

Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins

Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2

Structural basis of cyclin-dependent kinase activation by phosphorylation

Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E

SWISS-MODEL: An automated protein homology-modeling server

Chromosome association of minichromosome maintenance proteins in Drosophila endoreplication cycles

Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

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