Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
about
Motif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationShort linear motifs - ex nihilo evolution of protein regulationQuantitative framework for ordered degradation of APC/C substrates.Sequential replication-coupled destruction at G1/S ensures genome stability.Sgo1 recruits PP2A to chromosomes to ensure sister chromatid bi-orientation during mitosis.Spatiotemporal regulation of the anaphase-promoting complex in mitosisCell cycle proliferation decisions: the impact of single cell analyses.The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis.Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition.An APC/C-Cdh1 Biosensor Reveals the Dynamics of Cdh1 Inactivation at the G1/S TransitionEfficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkagesSubstrate Recognition by the Cdh1 Destruction Box Receptor Is a General Requirement for APC/CCdh1-mediated ProteolysisIncreased expression of Cks1 protein is associated with lymph node metastasis and poor prognosis in nasopharyngeal carcinoma.SLiMSearch: a framework for proteome-wide discovery and annotation of functional modules in intrinsically disordered regions.The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation.Detection and Analysis of Cell Cycle-Associated APC/C-Mediated Cellular Ubiquitylation In Vitro and In Vivo.Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex.Dynamic ubiquitin signaling in cell cycle regulation.Phosphorylation and dephosphorylation regulate APC/C(Cdh1) substrate degradation.Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulatorsBubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.Firing of Replication Origins Frees Dbf4-Cdc7 to Target Eco1 for Destruction.Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C).A reference-based protein degradation assay without global translation inhibitors.Degradation of Ndd1 by APC/C(Cdh1) generates a feed forward loop that times mitotic protein accumulation.How mitosis keeps itself in order.Control of DNA Replication Initiation by Ubiquitin
P2860
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P2860
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
description
2014 nî lūn-bûn
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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
@ast
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
@en
type
label
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
@ast
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
@en
prefLabel
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
@ast
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
@en
P2093
P2860
P50
P356
P1476
Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.
@en
P2093
Jennifer Y Hsiao
Scott A Foster
Vanessa A Van Voorhis
P2860
P356
10.1083/JCB.201402041
P407
P577
2014-10-06T00:00:00Z