Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses - Wikidata - awgldk - TriplyDB

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

http://www.wikidata.org/entity/Q28303382

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Cyclic di-GMP sensing via the innate immune signaling protein STING Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system Psychedelics and Immunomodulation: Novel Approaches and Therapeutic Opportunities Immunomodulatory functions of type I interferons The role of ubiquitylation in immune defence and pathogen evasion Intracellular nucleic acid sensors and autoimmunity Collaboration of Toll-like and RIG-I-like receptors in human dendritic cells: tRIGgering antiviral innate immune responses Transcriptional activation of the adenoviral genome is mediated by capsid protein VI Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation.miRNAs in the Pathogenesis of Systemic Lupus Erythematosus A network pharmacology study of Chinese medicine QiShenYiQi to reveal its underlying multi-compound, multi-target, multi-pathway mode of action RIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon production Intrinsic antiviral immunity Stable gene targeting in human cells using single-strand oligonucleotides with modified bases Potential of vesicular stomatitis virus as an oncolytic therapy for recurrent and drug-resistant ovarian cancer.Efficient size-independent chromosome delivery from yeast to cultured cell lines Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4.Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1 Human cytomegalovirus modulates monocyte-mediated innate immune responses during short-term experimental latency in vitro STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages.Subversion of host cellular functions by the apicomplexan parasites.Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity Dendritic-cell-based therapeutic cancer vaccines Sweeten PAMPs: Role of Sugar Complexed PAMPs in Innate Immunity and Vaccine Biology.NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses.Identification of small molecules with type I interferon inducing properties by high-throughput screening.DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.A STING-dependent innate-sensing pathway mediates resistance to corneal HSV-1 infection via upregulation of the antiviral effector tetherin The 3'-5' DNA exonuclease TREX1 directly interacts with poly(ADP-ribose) polymerase-1 (PARP1) during the DNA damage response.Human kinome analysis reveals novel kinases contributing to virus infection and retinoic-acid inducible gene I-induced type I and type III IFN gene expression.The mechanism of double-stranded DNA sensing through the cGAS-STING pathway STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells.STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer STING-dependent type I IFN production inhibits cell-mediated immunity to Listeria monocytogenes.A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant.Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway

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Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

http://www.wikidata.org/entity/Q28303382

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Innate immune DNA sensing path ...... ion and inflammatory responses

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Innate immune DNA sensing path ...... ion and inflammatory responses

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Innate immune DNA sensing path ...... ion and inflammatory responses

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Innate immune DNA sensing path ...... ion and inflammatory responses

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Innate immune DNA sensing path ...... ion and inflammatory responses

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Innate immune DNA sensing path ...... ion and inflammatory responses

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prefLabel

Innate immune DNA sensing path ...... ion and inflammatory responses

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Innate immune DNA sensing path ...... ion and inflammatory responses

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Innate immune DNA sensing path ...... ion and inflammatory responses

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J.COI.2010.12.015

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Current Opinion in Immunology

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Innate immune DNA sensing path ...... ion and inflammatory responses

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Glen N Barber

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A Toll-like receptor recognizes bacterial DNA

IFI16 is an innate immune sensor for intracellular DNA

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA

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10-20

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scholarly article

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5095636

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10.1016/J.COI.2010.12.015

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21239155

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