Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity - Wikidata - awgldk - TriplyDB

Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity

Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity

http://www.wikidata.org/entity/Q28305487

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COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ Autophagy and Apoptotic Crosstalk: Mechanism of Therapeutic Resistance in HER2-Positive Breast Cancer RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway Resveratrol induces growth arrest and apoptosis through activation of FOXO transcription factors in prostate cancer cells FOXO transcription factors at the interface between longevity and tumor suppression Bimodal regulation of FoxO3 by AKT and 14-3-3 Tight correlation between expression of the Forkhead transcription factor FOXM1 and HER2 in human breast cancer.Cardio-oncology in targeting the HER receptor family: the puzzle of different cardiotoxicities of HER2 inhibitors.FOXO transcription factors: their clinical significance and regulation.FOXOs, cancer and regulation of apoptosis The emerging role of the COP9 signalosome in cancer.Targeting nucleocytoplasmic transport in cancer therapy Nucleo-cytoplasmic transport as a therapeutic target of cancer 14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1.The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling.FoxO4 is the main forkhead transcriptional factor localized in the gastrointestinal tracts of pigs The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis.Insights into the beneficial effect of caloric/ dietary restriction for a healthy and prolonged life.COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis.Molecular mechanisms of cardiotoxicity induced by ErbB receptor inhibitor cancer therapeutics CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6 CDK inhibitor p57 (Kip2) is downregulated by Akt during HER2-mediated tumorigenicity.Curcumin induces G2/M arrest and triggers apoptosis via FoxO1 signaling in U87 human glioma cells Many forks in the path: cycling with FoxO.Forkhead transcription factors and ageing.MiR-150 promotes cellular metastasis in non-small cell lung cancer by targeting FOXO4.Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway.Replication of JC Virus DNA in the G144 Oligodendrocyte Cell Line Is Dependent Upon Akt.Profiling Cell Lines Nuclear Sub-proteome.Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells.Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age

P2860

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Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity

http://www.wikidata.org/entity/Q28305487

description

2005 nî lūn-bûn

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2005 թուականի Մարտին հրատարակուած գիտական յօդուած

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2005 թվականի մարտին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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Constitutively active FOXO4 in ...... s HER2-mediated tumorigenicity

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Constitutively active FOXO4 in ...... s HER2-mediated tumorigenicity

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Constitutively active FOXO4 in ...... s HER2-mediated tumorigenicity

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Heng-Yin Yang

http://www.w3.org/2001/XMLSchema#string

Huiling Yang

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Ruiying Zhao

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

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1924-1935

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5123027

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10.1038/SJ.ONC.1208352

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11

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24

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1004096893

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15688030

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