A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant
about
N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effectsN-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases.Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein foldingDe novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and femalesBiochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defectsThe biological functions of Naa10 - From amino-terminal acetylation to human diseaseNAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment.Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms.Expanding the Phenotype Associated with NAA10-Related N-Terminal Acetylation DeficiencyLoss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.Proteomic and genomic characterization of a yeast model for Ogden syndrome.The proteome under translational control.Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathwayMicroscopy-based Saccharomyces cerevisiae complementation model reveals functional conservation and redundancy of N-terminal acetyltransferases.Isolation of protein complexes from the model legume Medicago truncatula by tandem affinity purification in hairy root cultures.NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant - a case report.
P2860
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P2860
A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant
description
2014 nî lūn-bûn
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2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2014 թվականի օգոստոսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@ast
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@en
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@nl
type
label
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@ast
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@en
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@nl
prefLabel
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@ast
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@en
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@nl
P2860
P50
P3181
P356
P1476
A Saccharomyces cerevisiae mod ...... nsferase NAA10 Ser37Pro mutant
@en
P2860
P304
P3181
P356
10.1074/MCP.M113.035402
P407
P577
2014-08-01T00:00:00Z