Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein
about
Evolutionary and molecular facts link the WWC protein family to Hippo signalingA coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZAngiomotin is a novel Hippo pathway component that inhibits YAP oncoproteinStructures of YAP protein domains reveal promising targets for development of new cancer drugsHippo pathway-independent restriction of TAZ and YAP by angiomotinA Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue SarcomasStructural insights into the YAP and TEAD complexTargeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer TherapyEmerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancerThe Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionThe role of YAP transcription coactivator in regulating stem cell self-renewal and differentiationCrucial role for Mst1 and Mst2 kinases in early embryonic development of the mouseDeregulation of the Hippo pathway in mouse mammary stem cells promotes mammary tumorigenesis.Yes-associated protein 1 is activated and functions as an oncogene in meningiomas.The Hippo signaling pathway and translational opportunities for brain cancersMolecular evolution of the Yap/Yorkie proto-oncogene and elucidation of its core transcriptional program.The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesisThe Hippo pathway in disease and therapy: cancer and beyondProteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomasYes-associated protein expression in head and neck squamous cell carcinoma nodal metastasisYorkie promotes transcription by recruiting a histone methyltransferase complexControl of tissue growth and cell transformation by the Salvador/Warts/Hippo pathway.The ubiquitin E3 ligase ITCH enhances breast tumor progression by inhibiting the Hippo tumor suppressor pathway.Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response.Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador-Warts-Hippo pathwaySki regulates Hippo and TAZ signaling to suppress breast cancer progression.TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growthHippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest.The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domainYAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14.Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade.The induction of yes-associated protein expression after arterial injury is crucial for smooth muscle phenotypic modulation and neointima formation.ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer.Myocardin-Related Transcription Factor A and Yes-Associated Protein Exert Dual Control in G Protein-Coupled Receptor- and RhoA-Mediated Transcriptional Regulation and Cell Proliferation.A basal-like breast cancer-specific role for SRF-IL6 in YAP-induced cancer stemnessPML Surfs into HIPPO Tumor Suppressor Pathway.Negative correlation of ITCH E3 ubiquitin ligase and miRNA-106b dictates metastatic progression in pancreatic cancerYes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinomacAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.
P2860
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P2860
Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@ast
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@en
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@nl
type
label
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@ast
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@en
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@nl
prefLabel
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@ast
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@en
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@nl
P2093
P3181
P1433
P1476
Both TEAD-binding and WW domai ...... vity of yes-associated protein
@en
P2093
Joungmok Kim
Kun-Liang Guan
Zhi-Chun Lai
P304
P3181
P356
10.1158/0008-5472.CAN-08-2997
P407
P577
2009-02-01T00:00:00Z