Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension - Wikidata - awgldk - TriplyDB

Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension

Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension

http://www.wikidata.org/entity/Q28331116

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P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues Inside epoxyeicosatrienoic acids and cardiovascular disease The role of epoxyeicosatrienoic acids in the cardiovascular system Dihydroxyeicosatrienoic acids are potent activators of Ca(2+)-activated K(+) channels in isolated rat coronary arterial myocytes Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet Increased blood pressure in mice lacking cytochrome P450 2J5 The Use of Gene Ontology Term and KEGG Pathway Enrichment for Analysis of Drug Half-Life Vascular Endothelial Over-Expression of Human Soluble Epoxide Hydrolase (Tie2-sEH Tr) Attenuates Coronary Reactive Hyperemia in Mice: Role of Oxylipins and ω-Hydroxylases Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading.The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance.Eicosanomic profiling reveals dominance of the epoxygenase pathway in human amniotic fluid at term in spontaneous labor.Cytochrome P450 2J2: distribution, function, regulation, genetic polymorphisms and clinical significance.Inhibition of soluble epoxide hydrolase reduces food intake and increases metabolic rate in obese mice.Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase.Vascular endothelial overexpression of human CYP2J2 (Tie2-CYP2J2 Tr) modulates cardiac oxylipin profiles and enhances coronary reactive hyperemia in mice.Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.Evidence that 20-HETE contributes to the development of acute and delayed cerebral vasospasm.Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis.Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice.Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.Epoxyeicosatrienoic acids: formation, metabolism and potential role in tissue physiology and pathophysiology.Maternal and fetal epoxyeicosatrienoic acids in normotensive and preeclamptic pregnancies.20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension Epoxyeicosatrienoic acids affect electrolyte transport in renal tubular epithelial cells: dependence on cyclooxygenase and cell polarity.Identification and quantification of metabolites of arachidonic acid from cultures of endothelial cells by HPLC-MS2.14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha.Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor.14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition.Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications.Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels.Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A2A receptor and plasma oxylipins.Impact of genetic polymorphisms in CYP2C8 and rosiglitazone intake on the urinary excretion of dihydroxyeicosatrienoic acids.Two Pools of Epoxyeicosatrienoic Acids in Humans: Alterations in Salt-Sensitive Normotensive Subjects.Association between the soluble epoxide hydrolase gene and preeclampsia.Cytochrome P450: a novel system modulating Ca2+ channels and contraction in mammalian heart cells.

P2860

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P2860

Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension

http://www.wikidata.org/entity/Q28331116

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1990 nî lūn-bûn

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1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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1990 թվականի օգոստոսին հրատարակված գիտական հոդված

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1990年の論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年论文

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Endogenous biosynthesis of ara ...... pregnancy-induced hypertension

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Endogenous biosynthesis of ara ...... pregnancy-induced hypertension

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Endogenous biosynthesis of ara ...... pregnancy-induced hypertension

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Endogenous biosynthesis of ara ...... pregnancy-induced hypertension

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Endogenous biosynthesis of ara ...... pregnancy-induced hypertension

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Endogenous biosynthesis of ara ...... pregnancy-induced hypertension

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Proceedings of the National Academy of Sciences of the United States of America

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Endogenous biosynthesis of ara ...... pregnancy-induced hypertension

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D J Fitzgerald

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F Catella

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G A FitzGerald

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J A Lawson

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P2860

Platelet life-span in normal pregnancy and pre-eclampsia as determined by a non-radioisotope technique.

12(R)-hydroxyicosatetraenoic acid: a cytochrome-P450-dependent arachidonate metabolite that inhibits Na+,K+-ATPase in the cornea.

Metabolism of 20-hydroxyeicosatetraenoic acid by cyclooxygenase. Formation and identification of novel endothelium-dependent vasoconstrictor metabolites.

A study of angiotensin II pressor response throughout primigravid pregnancy.

Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct

Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids.

Effect of changes in dietary sodium on active electrolyte transport by erythrocytes at different stages of human pregnancy.

Metabolism of arachidonate through NADPH-dependent oxygenase of renal cortex

Arachidonic acid metabolism in isolated pancreatic islets. IV. Negative ion-mass spectrometric quantitation of monooxygenase product synthesis by liver and islets.

Inhibition of cyclooxygenase activity and platelet aggregation by epoxyeicosatrienoic acids. Influence of stereochemistry.

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2198572

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arterial hypertension

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