Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1 - Wikidata - awgldk - TriplyDB

Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1

Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1

http://www.wikidata.org/entity/Q28335917

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Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome Facile purification of honokiol and its antiviral and cytotoxic properties Structure-activity relationships and mode of action of 5-mercapto-substituted oligo- and polynucleotides as antitemplates inhibiting replication of human immunodeficiency virus type 1 Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3'-azido-3'-deoxythymidine Antiviral L-nucleosides specific for hepatitis B virus infection Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine Comparative analysis of anti-human immunodeficiency virus type 1 activities of dideoxynucleoside analogs in resting and activated peripheral blood mononuclear cells Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs Comparison of the antiviral activity of hydrophobic amino acid phosphoramidate monoesters of 2'3'-dideoxyadenosine (DDA) and 3'-azido-3'-deoxythymidine (AZT).PAMAM dendrimers and branched polyethyleneglycol (nanoparticles) prodrugs of (-)-beta-D-(2R, 4R)-dioxolane-thymine (DOT) and their anti-HIV activity.Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells.Pronucleotides: toward the in vivo delivery of antiviral and anticancer nucleotides.Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus.Antiviral activity and pharmacokinetics of 1-(2,3-dideoxy-2-fluoro-beta-L-glyceropent-2-enofuranosyl)cytosine.Development of a human immunodeficiency virus vector-based, single-cycle assay for evaluation of anti-integrase compounds Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: inhibition of de novo infection and activation of viral LTR.Antiretroviral therapy: reverse transcriptase inhibition.Synthesis of carbocyclic nucleoside analogs with five-membered heterocyclic nucleobases.Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells.Infectious amplification of wild-type human immunodeficiency virus from patients' lymphocytes and modulation by reverse transcriptase inhibitors in vitro.Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs.Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase.Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2',3'-dideoxy-2',2'-difluoro-4'-azanucleosides Antiretrovirals, Methamphetamine, and HIV-1 Envelope Protein gp120 Compromise Neuronal Energy Homeostasis in Association with Various Degrees of Synaptic and Neuritic Damage D- and L-2',3'-didehydro-2',3'-dideoxy-3'-fluoro-carbocyclic nucleosides: synthesis, anti-HIV activity and mechanism of resistance Manadomanzamines A and B: a novel alkaloid ring system with potent activity against mycobacteria and HIV-1.Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors.Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.New approaches for quantitating the inhibition of HIV-1 replication by antiviral drugs in vitro and in vivo.Synthesis and targeted delivery of an azidothymidine homodinucleotide conferring protection to macrophages against retroviral infection.New dinucleoside phosphonate derivatives as prodrugs of 3'-azido-3'-deoxythymidine and β-L-2',3'-dideoxy-3'-thiacytidine: synthesis and anti-HIV properties.Synthesis and evaluation of Janus type nucleosides as potential HCV NS5B polymerase inhibitors.Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5'-triphosphates Synthesis of purine modified 2'-C-methyl nucleosides as potential anti-HCV agents.

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P2860

Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1

http://www.wikidata.org/entity/Q28335917

description

1990 nî lūn-bûn

@nan

1990 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1990 թվականի հունիսին հրատարակված գիտական հոդված

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1990年の論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年论文

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name

Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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Antimicrobial Agents and Chemotherapy

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Activities of 3'-azido-3'-deox ...... immunodeficiency virus type 1

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D L Cannon

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E F Hahn

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G A Smith

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G C Hart

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J P Sommadossi

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M Y Xie

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R F Schinazi

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V Saalmann

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P2860

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

Synthesis and biological activity of several amino analogues of thymidine

Synergistic activity of granulocyte-macrophage colony-stimulating factor and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro

Nucleotide dimers suppress HIV expression in vitro

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

Combinations of isoprinosine and 3'-azido-3'-deoxythymidine in lymphocytes infected with human immunodeficiency virus type 1

Combinations of 3'-azido-3'-deoxythymidine (zidovudine) and phosphonoformate (foscarnet) against human immunodeficiency virus type 1 and cytomegalovirus replication in vitro

Uridine reverses the toxicity of 3'-azido-3'-deoxythymidine in normal human granulocyte-macrophage progenitor cells in vitro without impairment of antiretroviral activity

Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro

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1061-7

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10.1128/AAC.34.6.1061

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6

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34

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